Results 61 to 70 of about 8,163,121 (296)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Statistical inference of regulatory networks for circadian regulation [PDF]
, 2014 The work described in the present article is part of the TiMet project on linking the circadian clock to metabolism in plants. TiMet is a collaborative project (Grant Agreement 245143) funded by the European Commission FP7, in response to call FP7-KBBE ...
Aderhold, Andrej +2 more
core +1 more source
Scientific Reports, 2022 Accurate inference and prediction of gene regulatory network are very important for understanding dynamic cellular processes. The large-scale time series genomics data are helpful to reveal the molecular dynamics and dynamic biological processes of ...
Zhenyu Liu +7 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Directed partial correlation : inferring large-scale gene regulatory network through induced topology disruptions [PDF]
, 2011 Inferring regulatory relationships among many genes based on their temporal variation in transcript abundance has been a popular research topic. Due to the nature of microarray experiments, classical tools for time series analysis lose power since the ...
Li Chang-Tsun +8 more
core +2 more sources
Improving the Inference of Gene Expression Regulatory Networks with Data Aggregation Approach
مجله انفورماتیک سلامت و زیست پزشکی, 2020 Introduction: The major issue for the future of bioinformatics is the design of tools to determine the functions and all products of single-cell genes.
Atefeh Naseri +2 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reverse engineering gene regulatory networks [PDF]
IEEE Signal Processing Magazine, 2009 Statistical models for reverse engineering gene regulatory networks are surveyed in this article. To provide readers with a system-level view of the modeling issues in this research, a graphical modeling framework is proposed. This framework serves as the scaffolding on which the review of different models can be systematically assembled.
Yufei Huang 0001 +2 more
openaire +2 more sources
BMC Medical Genomics, 2008 Background Inflammation is a hallmark of many human diseases. Elucidating the mechanisms underlying systemic inflammation has long been an important topic in basic and clinical research. When primary pathogenetic events remains unclear due to its immense
Lan Chung-Yu +3 more
doaj +1 more source
Co-expression pan-network reveals genes involved in complex traits within maize pan-genome
BMC Plant Biology, 2022 Background With the advances in the high throughput next generation sequencing technologies, genome-wide association studies (GWAS) have identified a large set of variants associated with complex phenotypic traits at a very fine scale.
H. Busra Cagirici +2 more
doaj +1 more source