Results 71 to 80 of about 474,387 (314)
A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves [PDF]
, 2013 A model is presented describing the gene regulatory network surrounding three similar NAC transcription factors that have roles in Arabidopsis leaf senescence and stress responses. ANAC019, ANAC055 and ANAC072 belong to the same clade of NAC domain genes
Cooke, Emma J. +31 more
core +1 more source
BMC Medical Genomics, 2008 Background Inflammation is a hallmark of many human diseases. Elucidating the mechanisms underlying systemic inflammation has long been an important topic in basic and clinical research. When primary pathogenetic events remains unclear due to its immense
Lan Chung-Yu +3 more
doaj +1 more source
IEEE Access, 2023 The study of dynamic behavior can better understand the mechanism of genetic regulatory network. DNA is transcribed into mRNA and mRNA is translated into proteins. The process takes time to complete.
Yumei Lin, Yuan Ma, Yunxian Dai
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Improving the Inference of Gene Expression Regulatory Networks with Data Aggregation Approach
مجله انفورماتیک سلامت و زیست پزشکی, 2020 Introduction: The major issue for the future of bioinformatics is the design of tools to determine the functions and all products of single-cell genes.
Atefeh Naseri +2 more
doaj
Co-expression pan-network reveals genes involved in complex traits within maize pan-genome
BMC Plant Biology, 2022 Background With the advances in the high throughput next generation sequencing technologies, genome-wide association studies (GWAS) have identified a large set of variants associated with complex phenotypic traits at a very fine scale.
H. Busra Cagirici +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Deconstructing the pluripotency gene regulatory network [PDF]
Nature Cell Biology, 2018 Pluripotent stem cells can be isolated from embryos or derived by reprogramming. Pluripotency is stabilized by an interconnected network of pluripotency genes that cooperatively regulate gene expression. Here we describe the molecular principles of pluripotency gene function and highlight post-transcriptional controls, particularly those induced by RNA-
Mo Li, Juan Carlos Izpisua Belmonte
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Using large-scale perturbations in gene network reconstruction
, 2005 Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computationally feasible.
Andrew Pomiankowski +8 more
core +1 more source