Results 71 to 80 of about 789,865 (294)
IEEE Access, 2023 The study of dynamic behavior can better understand the mechanism of genetic regulatory network. DNA is transcribed into mRNA and mRNA is translated into proteins. The process takes time to complete.
Yumei Lin, Yuan Ma, Yunxian Dai
doaj +1 more source
Dissecting early regulatory relationships in the lamprey neural crest gene network [PDF]
, 2008 The neural crest, a multipotent embryonic cell type, originates at the border between neural and nonneural ectoderm. After neural tube closure, these cells undergo an epithelial–mesenchymal transition, migrate to precise, often distant locations, and ...
Basch +22 more
core +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Phenotypic switching in gene regulatory networks [PDF]
Proceedings of the National Academy of Sciences, 2014 Significance Phenotypes of an isogenic cell population are determined by states of low and high gene expression. These are often associated with multiple steady states predicted by deterministic models of gene regulatory networks. Gene expression is, however, regulated via stochastic molecular interactions at transcriptional and translational
Philipp, Thomas +2 more
openaire +2 more sources
Co-expression pan-network reveals genes involved in complex traits within maize pan-genome
BMC Plant Biology, 2022 Background With the advances in the high throughput next generation sequencing technologies, genome-wide association studies (GWAS) have identified a large set of variants associated with complex phenotypic traits at a very fine scale.
H. Busra Cagirici +2 more
doaj +1 more source
Entropy of complex relevant components of Boolean networks
, 2007 Boolean network models of strongly connected modules are capable of capturing the high regulatory complexity of many biological gene regulatory circuits.
A. Faure +6 more
core +1 more source
Bayesian variable selection and data integration for biological regulatory networks [PDF]
, 2006 A substantial focus of research in molecular biology are gene regulatory networks: the set of transcription factors and target genes which control the involvement of different biological processes in living cells.
Chen, Guang +2 more
core +6 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Improving the Inference of Gene Expression Regulatory Networks with Data Aggregation Approach
مجله انفورماتیک سلامت و زیست پزشکی, 2020 Introduction: The major issue for the future of bioinformatics is the design of tools to determine the functions and all products of single-cell genes.
Atefeh Naseri +2 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source