Results 71 to 80 of about 786,474 (343)
Transfer of a large gene regulatory apparatus to a new developmental address in echinoid evolution [PDF]
Of the five echinoderm classes, only the modern sea urchins (euechinoids) generate a precociously specified embryonic micromere lineage that ingresses before gastrulation and then secretes the biomineral embryonic skeleton.
Arenas-Mena +20 more
core +2 more sources
The study of dynamic behavior can better understand the mechanism of genetic regulatory network. DNA is transcribed into mRNA and mRNA is translated into proteins. The process takes time to complete.
Yumei Lin, Yuan Ma, Yunxian Dai
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Fluctuations in Gene Regulatory Networks as Gaussian Colored Noise
The study of fluctuations in gene regulatory networks is extended to the case of Gaussian colored noise. Firstly, the solution of the corresponding Langevin equation with colored noise is expressed in terms of an Ito integral.
Alon U. +9 more
core +1 more source
Dissecting early regulatory relationships in the lamprey neural crest gene network [PDF]
The neural crest, a multipotent embryonic cell type, originates at the border between neural and nonneural ectoderm. After neural tube closure, these cells undergo an epithelial–mesenchymal transition, migrate to precise, often distant locations, and ...
Basch +22 more
core +3 more sources
Co-expression pan-network reveals genes involved in complex traits within maize pan-genome
Background With the advances in the high throughput next generation sequencing technologies, genome-wide association studies (GWAS) have identified a large set of variants associated with complex phenotypic traits at a very fine scale.
H. Busra Cagirici +2 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Discovering Study-Specific Gene Regulatory Networks
Microarrays are commonly used in biology because of their ability to simultaneously measure thousands of genes under different conditions. Due to their structure, typically containing a high amount of variables but far fewer samples, scalable network analysis techniques are often employed.
Bo, V +5 more
openaire +6 more sources
An extended Kalman filtering approach to modeling nonlinear dynamic gene regulatory networks via short gene expression time series [PDF]
Copyright [2009] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liang, Y +4 more
core +1 more source
Improving the Inference of Gene Expression Regulatory Networks with Data Aggregation Approach
Introduction: The major issue for the future of bioinformatics is the design of tools to determine the functions and all products of single-cell genes.
Atefeh Naseri +2 more
doaj

