Results 21 to 30 of about 1,756,365 (358)
The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]
, 2016 Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M +5 more
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Nature Communications, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
HaoRan Tang +12 more
doaj +1 more source
Transposon variants and their effects on gene expression in arabidopsis [PDF]
, 2013 Transposable elements (TEs) make up the majority of many plant genomes. Their transcription and transposition is controlled through siRNAs and epigenetic marks including DNA methylation.
Smith, L.M., Wang, X., Weigel, D.
core +3 more sources
Production and characterization of eggs from hens with ovomucoid gene mutation
Poultry Science, 2021 Ovomucoid is a major egg white protein which is considered as the most dominant allergen in chicken eggs. Owing to the difficulty of separating ovomucoid from egg whites, researchers have adopted genetic deletion for development of hypoallergenic eggs ...
Takehiro Mukae +4 more
doaj +1 more source
CRISPR-Cas9-mediated functional dissection of 3'-UTRs. [PDF]
, 2017 Many studies using reporter assays have demonstrated that 3' untranslated regions (3'-UTRs) regulate gene expression by controlling mRNA stability and translation.
Ahituv, Nadav +6 more
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A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer. [PDF]
, 2015 Targeting specifically primary prostate cancer (PCa) cells for immune therapy, gene therapy or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique PCa biomarker and oncogene that has been widely studied.
Fradet, Yves +5 more
core +5 more sources
CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy
Viruses, 2018 Currently, a new gene editing tool—the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated (Cas) system—is becoming a promising approach for genetic manipulation at the genomic level.
Shuliang Chen, Xiao Yu, Deyin Guo
doaj +1 more source
Targeting casein kinase 1 for cancer therapy: current strategies and future perspectives
Frontiers in Oncology, 2023 Casein Kinase 1 (CK1) is a family of serine/threonine protein kinases that play a crucial role in various cellular processes, including cell proliferation, survival, and metabolism.
Ngo Hoang Long, Sook-Jeong Lee
doaj +1 more source
Plant Direct, 2019 Targeted integration of recombinant DNA fragments into plant genomes by DNA double‐strand break (DSB) repair mechanisms has become a powerful tool for precision engineering of crops.
Andreas Schiermeyer +17 more
doaj +1 more source
Chimeric nucleases stimulate gene targeting in human cells [PDF]
, 2002 Gene targeting is a powerful technique to introduce genetic change into the genome of eukaryotic cells. It is widely used to create defined mutations in murine embryonic stem cells and theoretically could be used to create or repair mutations in ...
Baltimore, David, Porteus, Matthew
core +2 more sources