Results 1 to 10 of about 239,079 (262)

Development of alternative gene transfer techniques for ex vivo and in vivo gene therapy in a canine model [PDF]

Regenerative Therapy, 2021
Introduction: Gene therapy have recently attracted much attention as a curative therapeutic option for inherited single gene disorders such as hemophilia.
Masashi Noda, Kohei Tatsumi, Hideto Matsui, Yasunori Matsunari, Takeshi Sato, Yasushi Fukuoka, Akitsu Hotta, Teruo Okano, Kimihiko Kichikawa, Mitsuhiko Sugimoto, Midori Shima, Kenji Nishio   +11 more
doaj   +2 more sources

Transferring of Exopolysaccharide (EPS) Gene Cluster from Rhizobium leguminosarum to Pseudomonas fluorescens by Horizontal Gene Transfer Techniques

Zanco Journal of Pure and Applied Sciences, 2021
To increase drought resistance of efficient plant growth promoting Psuedomonas  fluorescens isolated from Erbil governorate soils, exopolysaccharide (EPS) gene cluster was transferred from Rhizobium leguminosarum to P. fluorescens.
Karzan K. Mahmud, Aras Muhammad Khudhur
doaj   +5 more sources

Biomimetic Peptides: A New Generation of Gene Transfer Vectors [PDF]

مجله دانشکده پزشکی اصفهان, 2022
Gene therapy is a new approach that aims to modify defective genes or intracellular expression of therapeutic proteins, and this depends on the use of high-efficiency gene transfer systems.
Hooman Mahmoudi Aznaveh, Maryam Nikkhah
doaj   +1 more source

Interleukins, growth factors, and transcription factors are key targets for gene therapy in osteoarthritis: A scoping review

Frontiers in Medicine, 2023
ObjectiveOsteoarthritis (OA) is the most common degenerative joint disease, characterized by a progressive loss of cartilage associated with synovitis and subchondral bone remodeling.
Melanie Uebelhoer, Cécile Lambert, Juliane Grisart, Kilian Guse, Stanislav Plutizki, Yves Henrotin, Yves Henrotin, Yves Henrotin   +7 more
doaj   +1 more source

Optimal techniques for arterial gene transfer [PDF]

Cardiovascular Research, 1997
Cardiovascular gene therapy is becoming a clinical reality due to improved vectors, delivery systems and careful experimental validation studies. Nearly all cardiovascular diseases are amenable to gene therapy, but the optimal combination of vector, delivery system and therapeutic gene is likely to be unique to each application.
L J, Feldman, G, Steg
openaire   +2 more sources

Lymphocyte apoptosis: induction by gene transfer techniques [PDF]

Gene Therapy, 1997
Efficient gene transfer of lymphocytes has been shown to be extremely difficult. The molecular background for this gene transfer resistance is not completely understood. We reasoned that apoptosis may play a role in this gene transfer resistance of lymphocytes.
O, Ebert, S, Finke, A, Salahi, M, Herrmann, B, Trojaneck, P, Lefterova, E, Wagner, R, Kircheis, D, Huhn, F, Schriever, I G, Schmidt-Wolf   +10 more
openaire   +2 more sources

Gene Therapy Applications in Dentistry: A Review [PDF]

Journal of Clinical and Diagnostic Research, 2017
Gene therapy involves transfer of new genetic material or manipulation of the existing material for the purpose of treating human disease. It involves transfer of genetic material – ex vivo and in vivo and may conceivably revolutionize clinical practice ...
Dinesh Francis Swamy, Sapna Sada Raut Dessai, Elaine Savia Barretto, Kathleen Manuela Dsouza   +3 more
doaj   +1 more source

Vibropolyfection: coupling polymer-mediated gene delivery to mechanical stimulation to enhance transfection of adherent cells

Journal of Nanobiotechnology, 2022
Background With the success of recent non-viral gene delivery-based COVID-19 vaccines, nanovectors have gained some public acceptance and come to the forefront of advanced therapies.
Federica Ponti, Nina Bono, Luca Russo, Paolo Bigini, Diego Mantovani, Gabriele Candiani   +5 more
doaj   +1 more source

Cotton Biotechnology: An Efficient Gene Transfer Protocol via Agrobacterium tumefaciens for a Greater Transgenic Recovery

Journal of Natural Fibers, 2022
Due to its economic worth, cotton (Gossypium hirsutum L.) is grown in almost 70 countries and provides income for more than 250 million people. Therefore, producing cotton with having some desired characteristics that includes extended biotic and abiotic
Ibrahim Ilker Ozyigit, Ilhan Dogan, Yilmaz Kaya, Kasim Bajrovic, Nermin Gozukirmizi   +4 more
doaj   +1 more source

Calcium Based Non-viral Gene Delivery: An Overview of Methodology and Applications [PDF]

Acta Medica Iranica, 2010
Application of therapeutic gene transfer in the treatment of genetic diseases is a notable progress but there are some disadvantages and limitations in it. The process of overcoming these barriers is a drastic change in gene delivery.
Kianoush Khosravi-Darani, Mohamaad Reza Mozafari, Ladan Rashidi, Mehrdad Mohammadi   +3 more
doaj   +1 more source