Results 41 to 50 of about 582,689 (334)

Unintended Genomic Outcomes in Current and Next Generation GM Techniques: A Systematic Review

Plants, 2022
Classical genetic engineering and new genome editing techniques, especially the CRISPR/Cas technology, increase the possibilities for modifying the genetic material in organisms. These technologies have the potential to provide novel agricultural traits,
Philomena Chu, Sarah Zanon Agapito-Tenfen   +1 more
doaj   +1 more source

Application of recombinant DNA technology to studies on plant secondary metabolism [PDF]

, 2001
This review which is concerned with the application of recombinant DNA technology to studies on plant secondary metabolism, presents the more common plant transformation strategies and shows how these genetic approaches are being used in attempts to ...
Yeoman, Michael M., Zárate, Rafael
core   +1 more source

Synthetic biology and microdevices : a powerful combination [PDF]

, 2013
Recent developments demonstrate that the combination of microbiology with micro-and nanoelectronics is a successful approach to develop new miniaturized sensing devices and other technologies.
Marchal, Kathleen, Vanderleyden, Jos, Venken, Lyn   +2 more
core   +2 more sources

Gene Therapy in the Management of Erectile Dysfunction (ED): Past, Present, and Future

The Scientific World Journal, 2009
In the past, many researchers considered viral vectors to be the most promising candidates to transfer genetic material into the corpora for the treatment of erectile dysfunction. However, at present, no viral vectors have progressed to human trials.
Arnold Melman, Kelvin P. Davies
doaj   +1 more source

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles

Frontiers in Oncology, 2022
The basis of the conventional gene-centric view on tumor evolution is that vertically inherited mutations largely define the properties of tumor cells.
Gábor Valcz, Beáta Újvári, Edit I. Buzás, Edit I. Buzás, Edit I. Buzás, Tibor Krenács, Sándor Spisák, Ágnes Kittel, Zsolt Tulassay, Péter Igaz, Péter Igaz, Péter Igaz, István Takács, Béla Molnár, Béla Molnár   +14 more
doaj   +1 more source

A transfer-learning approach to feature extraction from cancer transcriptomes with deep autoencoders [PDF]

, 2019
Publicado en Lecture Notes in Computer Science.The diagnosis and prognosis of cancer are among the more challenging tasks that oncology medicine deals with.
A Bashiri, GE Hinton, I Guyon, J Bergstra, JN Weinstein, JS Parker, K Kourou, N Srivastava, SC Schuster, SJ Pan, Y LeCun, Y Saeys, Y Xiao, Z Wang   +13 more
core   +1 more source

Avian adeno-associated virus vector efficiently transduces neurons in the embryonic and post-embryonic chicken brain.

PLoS ONE, 2012
The domestic chicken is an attractive model system to explore the development and function of brain circuits. Electroporation-mediated and retrovirus (including lentivirus) vector-mediated gene transfer techniques have been widely used to introduce ...
Ryosuke Matsui, Yasuto Tanabe, Dai Watanabe   +2 more
doaj   +1 more source

An Overview of the Use of Neural Networks for Data Mining Tasks [PDF]

, 2012
In the recent years the area of data mining has experienced a considerable demand for technologies that extract knowledge from large and complex data sources.
Alberts B, Alpaydin E, Ando T, Blake CL, Bramer MA, Castanheira LG, Han J, Lu H, Mitchell M, Ni X, Quinlan RJ, Rumelhart DE, Shafer JC, Shendure J, Simić D, Stahl F, Steinwart I, Surjandari I, Wei JS, Widrow B, Witten IH, Zaslavsky B, Zhang D   +22 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length

Respiratory Research, 2010
Background Poor gene transfer efficiency has been a major problem in developing an effective gene therapy for cystic fibrosis (CF) airway disease. Lysophosphatidylcholine (LPC), a natural airway surfactant, can enhance viral gene transfer in animal ...
Anson Don S, Cmielewski Patricia, Parsons David W   +2 more
doaj   +1 more source