Results 51 to 60 of about 582,689 (334)

GENE TRANSFER MICROINJECTION AUTOMATION TECHNIQUE IN AQUATIC ANIMAL

open access: yesChinese Journal of Mechanical Engineering, 2006
Counterpoising the disadvantages of low-level injec- tion efficiency and survival rates of the cell microinjection for aquatic animal used widely today,the cell automatic injection technique used in aquatic animal gene transfer is researched. The methods for transporting,holding and injecting cells automatically are presented,the cell automatic ...
Liu Tian-jun, Hou Li-ya
openaire   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Aplication of Gene Transfer in Aquaculture

open access: yesJurnal Akuakultur Indonesia, 2003
Recently, global food security has become a hot issue by the public in national as well as out of the country. Aquacultural output will need to be increased several fold in order to meet the rising demands for fish in coming years as the increasing of ...
. Alimuddin   +3 more
doaj   +1 more source

TT2013 meeting report: the transgenic technology meeting visits Asia for the first time [PDF]

open access: yes, 2013
The 11th Transgenic Technology meeting was held in Guangzhou, China on 25th–27th February 2013. Over 300 scientists and students from round the world gathered to hear the latest developments in the technologies underpinning the creation of transgenic and
Strathdee, D., Whitelaw, C.B.A.
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Efficient Gene Transfer and Gene Editing in Sterlet (Acipenser ruthenus)

open access: yesFrontiers in Genetics, 2018
The sturgeon (Acipenseriformes) is an important farmed species because of its economical value. However, neither gene transfer nor gene editing techniques have been established in sturgeon for molecular breeding and gene functional study until now.
Ji Chen   +9 more
doaj   +1 more source

Generation of mutant pigs by lipofection-mediated genome editing in embryos

open access: yesScientific Reports, 2021
The specificity and efficiency of CRISPR/Cas9 gene-editing systems are determined by several factors, including the mode of delivery, when applied to mammalian embryos.
Maki Hirata   +10 more
doaj   +1 more source

Gene therapy in the management of oral cancer: Review of the literature [PDF]

open access: yes, 2008
Gene therapy essentially consists of introducing specific genetic material into target cells without producing toxic effects on surrounding tissue. Advances over recent decades in the surgical, radiotherapeutic and chemotherapeutic treatment of oral ...
Ayllón Barbellido, Sonia   +5 more
core  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Sonoporation-mediated gene transfer into adult rat dorsal root ganglion cells

open access: yesJournal of Biomedical Science, 2010
Background Gene transfer into many cell types has been successfully used to develop alternative and adjunct approaches to conventional medical treatment. However, effective transfection of postmitotic neurons remains a challenge.
Wu Chih-Hsien   +7 more
doaj   +1 more source

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