Results 41 to 50 of about 80,551 (349)

The use of anesthetics for cesarean section delivery in women in Duhok, Kurdistan region, Iraq

Journal of Ideas in Health, 2022
Background: Limited information is available on anesthetics that are preferred or used by anesthesiologists for cesarean section (CS) delivery in Kurdistan region, Iraq.
Rozheen Shukry Karam, Fouad K. Mohammad   +1 more
doaj   +1 more source

The free energy of biomembrane and nerve excitation and the role of anesthetics

, 2018
In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference ...
Heimburg, Thomas, Jackson, Andrew D., Music, Tea, Wang, Tian   +3 more
core   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A., Buscemi R., Karch S. B., Lanzarone A., Roccuzzo R., Zerbo S.   +5 more
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Biochemical parameters of silver catfish (Rhamdia quelen) after transport with eugenol or essential oil of Lippia alba added to the water [PDF]

, 2017
The transport of live fish is a routine practice in aquaculture and constitutes a considerable source of stress to the animals. The addition of anesthetic to the water used for fish transport can prevent or mitigate the deleterious effects of transport ...
A. G. Becker, ALMROTH B.C., AZAMBUJA C.R., B. Baldisserotto, B. M. Heinzmann, BALDISSEROTTO B., BECKER A.G., BECKER A.G., BENOVIT S.C., BLENAU W., BRADFORD M.M., BUEGE J.A., C. C. Menezes, C. C. Zeppenfeld, C. Toni, COOKE S.J., CUNHA M.A., CUNHA M.A., DUBOIS M., ELLMAN G.L., ELLMAN G.L., GONÇALVES A.F.N., GOYAL A.K., HABIG W.H., HARROWER J.R., HUDETZ A.G., INOUE L.A.K.A., INOUE L.A.K.A., J. Salbego, LEUNG L.S., LINTERN M.C., LOWRY O.H., LÓPEZ M.D., MATÉS J.M., MAZZANTI L., MOMMSEN T.P., PANKHURST N.W., PARODI T.V., ROSS L.G., ROUBACH R., SALBEGO J., SALBEGO J., TONI C., UNGVARI Z., V. L. Loro, VALE T.G., VALE T.G., VILLARES JUNIOR G.A., YAN L.J., YONAR M.E., ZAHL I.H.   +50 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

General anesthetic binding mode via hydration with weak affinity and molecular discrimination: General anesthetic dissolution in interfacial water of the common binding site of GABAA receptor

Biophysics and Physicobiology, 2023
The GABAA receptor (GABAAR) is a target channel for the loss of awareness of general anesthesia. General anesthetic (GA) spans a wide range of chemical structures, such as monatomic molecules, barbital acids, phenols, ethers, and alkanes.
Tomoyoshi Seto
doaj   +1 more source

Cardiac output and the pharmacology of general anesthetics: a narrative review

Colombian Journal of Anesthesiology, 2023
The relationship between cardiac output and anesthetic drugs is important to anesthesiologists, since cardiac output determines the speed with which a drug infused into the bloodstream reaches its target and the intensity of the drug’s effect.
Elena Simón-Polo, Jose Vicente Catalá-Ripoll, José Ángel Monsalve-Naharro, Manuel Gerónimo-Pardo   +3 more
doaj   +1 more source

Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]

, 2008
Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A., Dougherty, Dennis A., Eastwood, Amy L., Horn, Richard   +3 more
core   +2 more sources

Are Local Anesthetics and General Anesthetics Different? [PDF]

Biophysical Journal, 2014
It is widely believed that general and local anesthetics act by different mechanisms. While there is general agreement that the mode of action of general anesthetics is poorly understood, local anesthetics are believed to block voltage-gated sodium channels and thereby affect action potentials in nerves.
Sasse-Middelhoff, Henrike, Zecchi, Karis, Heimburg, Thomas   +2 more
openaire   +1 more source