Results 1 to 10 of about 4,146,284 (322)
Theory in Biosciences, 2008 In order to describe a cell at molecular level, a notion of a "gene" is neither necessary nor helpful. It is sufficient to consider the molecules (i.e., chromosomes, transcripts, proteins) and their interactions to describe cellular processes. The downside of the resulting high resolution is that it becomes very tedious to address features on the ...
Prohaska, Sonja, Stadler, Peter F
openaire +3 more sources
Journal of Neuroinflammation, 2023 Background Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more females than males.
Sarah R. Ocañas +14 more
doaj +1 more source
Journal of Immunology Research, 2022 Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu +7 more
doaj +1 more source
Journal of Immunology Research, 2022 Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun +8 more
doaj +1 more source
Gene Complexity and Gene Duplicability [PDF]
Current Biology, 2005 Eukaryotic genes are on average more complex than prokaryotic genes in terms of expression regulation, protein length, and protein-domain structure [1-5]. Eukaryotes are also known to have a higher rate of gene duplication than prokaryotes do [6, 7]. Because gene duplication is the primary source of new genes [], the average gene complexity in a genome
Xionglei He, Jianzhi Zhang
openaire +3 more sources
Virology Journal, 2020 Background Nontuberculous mycobacterial (NTM) infections are increasing in prevalence, with current estimates suggesting that over 100,000 people in the United States are affected each year.
Cody Glickman +5 more
doaj +1 more source
A jornada da decisão do consumo de música na era digital por parte do consumidor jovem
Diálogo com a Economia Criativa, 2020 Este artigo buscou analisar como se dá a jornada de decisão dos jovens cariocas com alto capital cultural, no que tange ao consumo de música popular. Mais especificamente, buscou-se identificar as etapas e influências que ocorrem na jornada de decisão ...
Cecilia Mattoso, Felipe Genes
doaj +1 more source
Simulation study and comparative evaluation of viral contiguous sequence identification tools
BMC Bioinformatics, 2021 Background Viruses, including bacteriophages, are important components of environmental and human associated microbial communities. Viruses can act as extracellular reservoirs of bacterial genes, can mediate microbiome dynamics, and can influence the ...
Cody Glickman +2 more
doaj +1 more source
Vulnerability genes or plasticity genes? [PDF]
Molecular Psychiatry, 2009 The classic diathesis-stress framework, which views some individuals as particularly vulnerable to adversity, informs virtually all psychiatric research on behavior-gene-environment (G x E) interaction. An alternative framework of 'differential susceptibility' is proposed, one which regards those most susceptible to adversity because of their genetic ...
Belsky, J +5 more
openaire +4 more sources
FlyBase: genes and gene models [PDF]
Nucleic Acids Research, 2004 FlyBase (http://flybase.org) is the primary repository of genetic and molecular data of the insect family Drosophilidae. For the most extensively studied species, Drosophila melanogaster, a wide range of data are presented in integrated formats.
Rachel Drysdale, Madeline A. Crosby
openaire +3 more sources