Results 1 to 10 of about 6,888,444 (358)

Predicting synchronized gene coexpression patterns from fibration symmetries in gene regulatory networks in bacteria [PDF]

open access: yesBMC Bioinformatics 22, 363 (2021), 2021
Background: Gene regulatory networks coordinate the expression of genes across physiological states and ensure a synchronized expression of genes in cellular subsystems, critical for the coherent functioning of cells. Here we address the questions whether it is possible to predict gene synchronization from network structure alone.
arxiv   +1 more source

Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

open access: yesJournal of Neuroinflammation, 2023
Background Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more females than males.
Sarah R. Ocañas   +14 more
doaj   +1 more source

Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation

open access: yesJournal of Immunology Research, 2022
Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu   +7 more
doaj   +1 more source

Prospects of reinforcement learning for the simultaneous damping of many mechanical modes [PDF]

open access: yes, 2020
We apply adaptive feedback for the partial refrigeration of a mechanical resonator, i.e. with the aim to simultaneously cool the classical thermal motion of more than one vibrational degree of freedom.
Asjad, Muhammad   +2 more
core   +3 more sources

Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis

open access: yesJournal of Immunology Research, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun   +8 more
doaj   +1 more source

Characterization of integrated prophages within diverse species of clinical nontuberculous mycobacteria

open access: yesVirology Journal, 2020
Background Nontuberculous mycobacterial (NTM) infections are increasing in prevalence, with current estimates suggesting that over 100,000 people in the United States are affected each year.
Cody Glickman   +5 more
doaj   +1 more source

Atomic entanglement generation with reduced decoherence via four-wave mixing [PDF]

open access: yes, 2006
In most proposals for the generation of entanglement in large ensembles of atoms via projective measurements, the interaction with the vacuum is responsible for both the generation of the signal that is detected and the spin depolarization or decoherence.
Berman, P. R., Genes, C.
core   +2 more sources

Strong coupling and long-range collective interactions in optomechanical arrays [PDF]

open access: yes, 2012
We investigate the collective optomechanics of an ensemble of scatterers inside a Fabry-Perot resonator and identify an optimized configuration where the ensemble is transmissive, in contrast with the usual reflective optomechanics approach.
Dantan, Aurélien   +2 more
core   +2 more sources

Gene Function Prediction with Gene Interaction Networks: A Context Graph Kernel Approach [PDF]

open access: yesIEEE Transactions on Information Technology in Biomedicine, 2010, 2022
Predicting gene functions is a challenge for biologists in the post genomic era. Interactions among genes and their products compose networks that can be used to infer gene functions. Most previous studies adopt a linkage assumption, i.e., they assume that gene interactions indicate functional similarities between connected genes.
arxiv   +1 more source

Simulation study and comparative evaluation of viral contiguous sequence identification tools

open access: yesBMC Bioinformatics, 2021
Background Viruses, including bacteriophages, are important components of environmental and human associated microbial communities. Viruses can act as extracellular reservoirs of bacterial genes, can mediate microbiome dynamics, and can influence the ...
Cody Glickman   +2 more
doaj   +1 more source

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