Results 1 to 10 of about 11,860,410 (381)

SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways [PDF]

Nature Network Boston, 2020
We investigated SARS-CoV-2 potential tropism by surveying expression of viral entry-associated genes in single-cell RNA-sequencing data from multiple tissues from healthy human donors. We co-detected these transcripts in specific respiratory, corneal and
W. Sungnak, N. Huang, C. Bécavin, M. Berg, R. Queen, Monika Litviňuková, Carlos Talavera-López, H. Maatz, D. Reichart, F. Sampaziotis, Kaylee B. Worlock, Masahiro Yoshida, Josephine L. Barnes, Nicholas E. Pascal Alvis Joseph Tushar J. Thu Elizabeth Oli Banovich Barbry Brazma Collin Desai Duong Eickelbe, N. Banovich, P. Barbry, A. Brazma, J. Collin, T. Desai, T. Duong, O. Eickelberg, C. Falk, M. Farzan, I. Glass, Ravindra K. Gupta, M. Haniffa, P. Horváth, N. Hubner, Deborah T. Hung, N. Kaminski, M. Krasnow, J. Kropski, Malte Kuhnemund, M. Lako, Haeock Lee, S. Leroy, Sten Linnarson, J. Lundeberg, K. Meyer, Zhichao Miao, A. Misharin, M. Nawijn, M. Nikolić, M. Noseda, J. Ordovas-Montañes, G. Oudit, D. Pe’er, J. Powell, S. Quake, J. Rajagopal, P. R. Tata, E. Rawlins, A. Regev, P. Reyfman, O. Rozenblatt-Rosen, K. Saeb‐Parsy, C. Samakovlis, H. Schiller, J. Schultze, M. Seibold, C. Seidman, J. Seidman, A. Shalek, D. Shepherd, J. Spence, A. Spira, Xin Sun, S. Teichmann, Fabian J Theis, Alexander M. Tsankov, L. Vallier, M. van den Berge, J. Whitsett, R. Xavier, Yan Xu, L. Zaragosi, Darin Zerti, Hongbo Zhang, Kun Zhang, M. Rojas, Francisco Figueiredo   +80 more
semanticscholar   +1 more source

Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease

Journal of Neuroinflammation, 2023
Background Microglia, the brain’s principal immune cells, have been implicated in the pathogenesis of Alzheimer’s disease (AD), a condition shown to affect more females than males.
Sarah R. Ocañas, Kevin D. Pham, Jillian E. J. Cox, Alex W. Keck, Sunghwan Ko, Felix A. Ampadu, Hunter L. Porter, Victor A. Ansere, Adam Kulpa, Collyn M. Kellogg, Adeline H. Machalinski, Manu A. Thomas, Zsabre Wright, Ana J. Chucair-Elliott, Willard M. Freeman   +14 more
doaj   +1 more source

Prospects of reinforcement learning for the simultaneous damping of many mechanical modes [PDF]

, 2020
We apply adaptive feedback for the partial refrigeration of a mechanical resonator, i.e. with the aim to simultaneously cool the classical thermal motion of more than one vibrational degree of freedom.
Asjad, Muhammad, Genes, Claudiu, Sommer, Christian   +2 more
core   +3 more sources

Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation

Journal of Immunology Research, 2022
Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy with poor prognosis worldwide. Emerging evidences demonstrated critical roles of lipid de novo synthesis in HCC progression, yet its regulatory mechanisms are not fully ...
Lei Zhu, Kai X. Zhou, Ming Z. Ma, Lin L. Yao, Yan L. Zhang, Hui Li, Chang Du, Xiao M. Yang   +7 more
doaj   +1 more source

Diet-Induced Obesity Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma via CX3CL1/CX3CR1 Axis

Journal of Immunology Research, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers, and the patients are generally diagnosed with distant metastasis. Liver is one of the preferred organs of distant metastasis, and liver metastasis is the leading cause of ...
Yue Sun, Xiao-Xin Zhang, Shan Huang, Hong Pan, Yan-Zhi Gai, Yao-Qi Zhou, Lei Zhu, Hui-Zhen Nie, Dong-Xue Li   +8 more
doaj   +1 more source

KEGG: Kyoto Encyclopedia of Genes and Genomes

Nucleic Acids Res., 2000
KEGG (Kyoto Encyclopedia of Genes and Genomes) is a knowledge base for systematic analysis of gene functions, linking genomic information with higher order functional information.
M. Kanehisa, S. Goto
semanticscholar   +1 more source

Characterization of integrated prophages within diverse species of clinical nontuberculous mycobacteria

Virology Journal, 2020
Background Nontuberculous mycobacterial (NTM) infections are increasing in prevalence, with current estimates suggesting that over 100,000 people in the United States are affected each year.
Cody Glickman, Sara M. Kammlade, Nabeeh A. Hasan, L. Elaine Epperson, Rebecca M. Davidson, Michael Strong   +5 more
doaj   +1 more source

Atomic entanglement generation with reduced decoherence via four-wave mixing [PDF]

, 2006
In most proposals for the generation of entanglement in large ensembles of atoms via projective measurements, the interaction with the vacuum is responsible for both the generation of the signal that is detected and the spin depolarization or decoherence.
Berman, P. R., Genes, C.
core   +2 more sources

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Genome Biology, 2002
BackgroundGene-expression analysis is increasingly important in biological research, with real-time reverse transcription PCR (RT-PCR) becoming the method of choice for high-throughput and accurate expression profiling of selected genes.
J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, F. Speleman   +6 more
semanticscholar   +1 more source

A jornada da decisão do consumo de música na era digital por parte do consumidor jovem

Diálogo com a Economia Criativa, 2020
Este artigo buscou analisar como se dá a jornada de decisão dos jovens cariocas com alto capital cultural, no que tange ao consumo de música popular. Mais especificamente, buscou-se identificar as etapas e influências que ocorrem na jornada de decisão ...
Cecilia Mattoso, Felipe Genes
doaj   +1 more source