Results 161 to 170 of about 142,631 (286)

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

A stage specific NETs-related signature in alcoholic steatohepatitis: from molecular subtyping to therapeutic vulnerabilities. [PDF]

Front Immunol
Gao W, Lin Z, Bao Y, Liu M, Ma G, Chen X, Yu S, Zeng Y.   +7 more
europepmc   +1 more source

Comparison of the effectiveness, safety and tolerability of Perampanel and Levetiracetam as monotherapy in Chinese patients with focal‐onset seizures: A single‐center, ambispective, open‐label, real‐world observational study

Epilepsia Open, EarlyView.
Abstract Objective To compare the effectiveness and safety of Perampanel (PER) and Levetiracetam (LEV) as monotherapy in Chinese patients with focal‐onset seizures (FOS). Methods This is a single‐center, ambispective, open‐label, real‐world observational study.
Haiyan Ma, Rui Zhang, Yan Zhang, Honghao Xu, Xuefeng Qu, Yiqing Yang, Jiajia Li, Lu Yang, Qigang Zhou, Haitao Zhu   +9 more
wiley   +1 more source

GSTA1 deficiency drives neuroendocrine differentiation via TNFRSF13B/c-FOS/CHGA axis in prostate cancer. [PDF]

Int J Biol Sci
Qian J, Luo Y, Fu Y, Diao W, Ding Q, Chen W, Qiu X, Guo H.   +7 more
europepmc   +1 more source

The Fos-related antigen 1–JUNB/activator protein 1 transcription complex, a downstream target of signal transducer and activator of transcription 3, induces T helper 17 differentiation and promotes experimental autoimmune arthritis [PDF]

, 2017
et al,, Kim, Woo Kyung
core   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source

Multi-Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring. [PDF]

J Cachexia Sarcopenia Muscle
Liu R, She J, Li X, Yan Y, Mo J, Sheng J, Yang H, Huang H.   +7 more
europepmc   +1 more source

Neoarchean Arc Magmatism and Crust Recycling in the Northern Marginal Zone of the Limpopo Complex, Zimbabwe: New Insights From Zircon U‐Pb‐Hf Isotopes of a Charnockite Suite

Geological Journal, EarlyView.
Charnockites with 2691–2607 Ma magmatic ages from the NMZ show arc‐magmatic geochemical signatures. They correspond to the lower‐crustal equivalent of the Chilimanzi Suite Granite in the Zimbabwe Craton. Lu‐Hf isotopic data of magmatic zircons show negative εHf(t) values (−11.18 to −2.20) with TDMC ages of 3699–3158 Ma, suggesting their protolith ...
Toshiaki Tsunogae, Md. Sazzadur Rahman, Gao Pin, M. Santosh, Wataru Fujisaki, Sam Uthup, Prince Mandingaisa   +6 more
wiley   +1 more source

FOS and JUN regulate oxidative stress and steroidogenesis in human aldosterone-producing adenomas. [PDF]

Redox Biol
Wei J, Duregon E, Papotti MG, Knösel T, Bidlingmaier M, Sbiera S, Reincke M, Williams TA.   +7 more
europepmc   +1 more source