Results 1 to 10 of about 5,454,892 (222)

Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification

PLoS Genetics, 2022
Homeobox genes are prominent regulators of neuronal identity, but the extent to which their function has been probed in animal nervous systems remains limited.
Molly B. Reilly, Tessa Tekieli, Cyril Cros, G. Robert Aguilar, James Lao, Itai Antoine Toker, Berta Vidal, Eduardo Leyva-Díaz, Abhishek Bhattacharya, Steven J. Cook, Jayson J. Smith, Ismar Kovacevic, Burcu Gulez, Robert W. Fernandez, Elisabeth F. Bradford, Yasmin H. Ramadan, Paschalis Kratsios, Zhirong Bao, Oliver Hobert   +18 more
doaj   +3 more sources

The Homeobox Genes of Caenorhabditis elegans and Insights into Their Spatio-Temporal Expression Dynamics during Embryogenesis. [PDF]

PLoS ONE, 2015
Homeobox genes play crucial roles for the development of multicellular eukaryotes. We have generated a revised list of all homeobox genes for Caenorhabditis elegans and provide a nomenclature for the previously unnamed ones.
Jürgen Hench, Johan Henriksson, Akram M Abou-Zied, Martin Lüppert, Johan Dethlefsen, Krishanu Mukherjee, Yong Guang Tong, Lois Tang, Umesh Gangishetti, David L Baillie, Thomas R Bürglin   +10 more
doaj   +2 more sources

Calcisponges have a ParaHox gene and dynamic expression of dispersed NK homeobox genes [PDF]

Nature, 2014
This study was funded by the Sars Centre core budget to M. Adamska. Sequencing was performed at the Norwegian High Throughput Sequencing Centre funded by the Norwegian Research Council. O.M.R. and D.E.K.F.
A Saudemont, B Fahey, B Li, C Larroux, C Larroux, D Chourrout, D Darriba, DEK Ferrier, GN Luke, H-C Seo, J Garcia-Fernàndez, JF Ryan, JHL Hui, JHL Hui, KJ Peterson, M Boetzer, M Srivastava, MG Grabherr, N Takatori, O Mendivil Ramos, R Luo, S Amano, S Anders, S Fortunato, S Leininger, SA Fortunato, TM Keane, Y-F Zhong   +27 more
core   +3 more sources

The dynamics of vertebrate homeobox gene evolution: gain and loss of genes in mouse and human lineages

BMC Evolutionary Biology, 2011
Background Homeobox genes are a large and diverse group of genes, many of which play important roles in transcriptional regulation during embryonic development.
Holland Peter WH, Zhong Ying-fu
doaj   +2 more sources

Characterization of Rice Homeobox Genes, OsHOX22 and OsHOX24, and Over-expression of OsHOX24 in Transgenic Arabidopsis Suggest their Role in Abiotic Stress Response

Frontiers in Plant Science, 2016
Homeobox transcription factors are well known regulators of plant growth and development. In this study, we carried out functional analysis of two candidate stress-responsive HD-ZIP I class homeobox genes from rice, OsHOX22 and OsHOX24.
Annapurna eBhattacharjee, Jitendra Paul Khurana, Mukesh eJain, Mukesh eJain   +3 more
doaj   +2 more sources

Classification and nomenclature of all human homeobox genes

BMC Biology, 2007
Background The homeobox genes are a large and diverse group of genes, many of which play important roles in the embryonic development of animals. Increasingly, homeobox genes are being compared between genomes in an attempt to understand the evolution of
Bruford Elspeth A, Booth H, Holland Peter WH   +2 more
doaj   +2 more sources

NKL homeobox genes in leukemia [PDF]

Leukemia, 2011
NK-like (NKL) homeobox genes code for transcription factors, which can act as key regulators in fundamental cellular processes. NKL genes have been implicated in divergent types of cancer. In this review, we summarize the involvement of NKL genes in cancer and leukemia in particular.
Homminga, Irene, Meijerink, Jules P. P., Pieters, Rob   +2 more
openaire   +5 more sources

Evolution of homeobox genes

WIREs Developmental Biology, 2012
AbstractMany homeobox genes encode transcription factors with regulatory roles in animal and plant development. Homeobox genes are found in almost all eukaryotes, and have diversified into 11 gene classes and over 100 gene families in animal evolution, and 10 to 14 gene classes in plants.
P. Holland
openaire   +3 more sources

A conserved cluster of three PRD-class homeobox genes (homeobrain, rx and orthopedia) in the Cnidaria and Protostomia

EvoDevo, 2010
Background Homeobox genes are a superclass of transcription factors with diverse developmental regulatory functions, which are found in plants, fungi and animals.
Mazza Maureen E, Pang Kevin, Reitzel Adam M, Martindale Mark Q, Finnerty John R   +4 more
doaj   +2 more sources

Functions of LIM-homeobox genes

Trends in Genetics, 2000
Homeobox genes play fundamental roles in development. They can be subdivided into several subfamilies, one of which is the LIM-homeobox subfamily. The primary structure of LIM-homeobox genes has been remarkably conserved through evolution. Have their functions similarly been conserved?
O, Hobert, H, Westphal
openaire   +3 more sources