Results 11 to 20 of about 5,454,912 (236)
Conserved pleiotropy of an ancient plant homeobox gene uncovered by cis-regulatory dissection.
Cell, 2021 Divergence of gene function is a hallmark of evolution, but assessing functional divergence over deep time is not trivial. The few alleles available for cross-species studies often fail to expose the entire functional spectrum of genes, potentially ...
Anat Hendelman +12 more
semanticscholar +3 more sources
Homeobox Genes in Cancers: From Carcinogenesis to Recent Therapeutic Intervention
Frontiers in Oncology, 2021 The homeobox (HOX) genes encoding an evolutionarily highly conserved family of homeodomain-containing transcriptional factors are essential for embryogenesis and tumorigenesis.
Yangyang Feng +7 more
semanticscholar +1 more source
The Role of NKL Homeobox Genes in T-Cell Malignancies
Biomedicines, 2021 Homeobox genes encode transcription factors controlling basic developmental processes. The homeodomain is encoded by the homeobox and mediates sequence-specific DNA binding and interaction with cofactors, thus operating as a basic regulatory platform ...
Stefan Nagel
doaj +1 more source
Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes.
Cell, 1994 Y. Sasai +5 more
semanticscholar +3 more sources
CUT homeobox genes: transcriptional regulation of neuronal specification and beyond
Frontiers in Cellular Neuroscience, 2023 CUT homeobox genes represent a captivating gene class fulfilling critical functions in the development and maintenance of multiple cell types across a wide range of organisms.
Eduardo Leyva-Díaz
doaj +1 more source
Endocrine Regulations, 2023 Objective. Homeobox genes play a fundamental role in the embryogenesis, but some of them have been linked to oncogenesis. The present study is aimed to investigate the impact of glucose and glutamine deprivations on the expression of homeobox genes such ...
Krasnytska Dariia O. +8 more
doaj +1 more source
Hemato, 2022 Homeobox genes encode transcription factors which control basic processes in development and differentiation. Concerning the sequence conservation in their homeobox, these genes are arranged into particular groups sharing evolutionary ancestry and ...
Stefan Nagel
doaj +1 more source
Genome-wide analysis of homeobox gene family in legumes: identification, gene duplication and expression profiling. [PDF]
PLoS ONE, 2015 Homeobox genes encode transcription factors that are known to play a major role in different aspects of plant growth and development. In the present study, we identified homeobox genes belonging to 14 different classes in five legume species, including ...
Annapurna Bhattacharjee +3 more
doaj +1 more source
An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. [PDF]
PLoS ONE, 2015 Here we used predictive gene expression signatures within a multi-species framework to identify the genes that underlie cardiac cell fate decisions in differentiating embryonic stem cells.
Brian W Busser +5 more
doaj +1 more source
Diagnostics, 2023 Homeobox genes serve as master regulatory transcription factors that regulate gene expression during embryogenesis. A homeobox gene may have either tumor-promoting or tumor-suppressive properties depending on the specific organ or cell lineage where it ...
Fee-Wai Chin +2 more
doaj +1 more source