Results 11 to 20 of about 232,012 (258)
Data on haplotype-supported immunoglobulin germline gene inference
Data in Brief, 2017 Data that defines IGHV (immunoglobulin heavy chain variable) germline gene inference using sequences of IgM-encoding transcriptomes obtained by Illumina MiSeq sequencing technology are described.
Ufuk Kirik +3 more
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A comprehensive analysis of immunoglobulin heavy chain genes in the Bactrian camel (Camelus bactrianus) [PDF]
Frontiers of Agricultural Science and Engineering, 2015 Heavy chain only antibodies (HCAbs) represent a rare type of antibody that is devoid of light chains and the CH1 domain that have been reported in cartilaginous fish and camelids.
Zuoxiang LIANG,Tao WANG,Yi SUN,Wenlong YANG,Zhihong LIU,Jing FEI,Ying GUO,Qingwei MA,Qingjie PAN,Liming REN
doaj +1 more source
The Determinants of B Cell Receptor Signaling as Prototype Molecular Biomarkers of Leukemia
Frontiers in Oncology, 2021 Advanced genome-wide association studies (GWAS) identified several transforming mutations in susceptible loci which are recognized as valuable prognostic markers in chronic lymphocytic leukemia (CLL) and B cell lymphoma (BCL).
Antonella Nicolò +3 more
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Gene expression signatures associated with chronic endometritis revealed by RNA sequencing
Frontiers in Medicine, 2023 IntroductionChronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by the infiltration of plasma cells in the endometrial stroma.
Kyoko Oshina +10 more
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Somatic hypermutation of immunoglobulin and non–immunoglobulin genes [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001 Somatic hypermutation (SHM) of immunoglobulin (Ig) genes is a highly specific mechanism restricted to B lymphocytes during only a few cell generations. Data presented here suggest that transcription of the target genes is required, but not sufficient for SHM. Presumably, cis –acting elements,
U, Storb, H M, Shen, N, Michael, N, Kim
openaire +2 more sources
Characterization of chicken spleen transcriptome after infection with Salmonella enterica serovar Enteritidis. [PDF]
PLoS ONE, 2012 In this study we were interested in identification of new markers of chicken response to Salmonella Enteritidis infection. To reach this aim, gene expression in the spleens of naive chickens and those intravenously infected with S.
Marta Matulova +7 more
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BMC Biotechnology, 2011 Background Molecular cloning of functional immunoglobulin genes from single plasma cells is one of the most promising technologies for the rapid development of monoclonal antibody drugs. However, the proper insertion of PCR-amplified immunoglobulin genes
Isobe Masaharu +2 more
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Physical map and one-megabase sequencing of the human immunoglobulin lambda locus
Genetics and Molecular Biology, 1998 The human immunoglobulin lambda (IGL) locus is located on chromosome 22q11.1-q11.2 and contains the genes responsible for the immunoglobulin lambda light chains. This locus was recently mapped (physical map) and its 1-Mb DNA totally sequenced.
Geraldo A.S. Passos Jr.
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Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus. [PDF]
PLoS ONE, 2014 Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative ...
Jenni Liljavirta +4 more
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Fungicidal activity of peptides encoded by immunoglobulin genes
Scientific Reports, 2017 Evidence from previous works disclosed the antimicrobial, antiviral, anti-tumour and/or immunomodulatory activity exerted, through different mechanisms of action, by peptides expressed in the complementarity-determining regions or even in the constant ...
Luciano Polonelli +8 more
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