Results 21 to 30 of about 353,198 (303)
The antibody loci of the domestic goat (Capra hircus) [PDF]
, 2018 The domestic goat (Capra hircus) is an important ruminant species both as a source of antibody-based reagents for research and biomedical applications and as an economically important animal for agriculture, particularly for developing nations that ...
Bickhart, Derek M. +4 more
core +1 more source
Gene expression signatures associated with chronic endometritis revealed by RNA sequencing
Frontiers in Medicine, 2023 IntroductionChronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by the infiltration of plasma cells in the endometrial stroma.
Kyoko Oshina +10 more
doaj +1 more source
Characterization of chicken spleen transcriptome after infection with Salmonella enterica serovar Enteritidis. [PDF]
PLoS ONE, 2012 In this study we were interested in identification of new markers of chicken response to Salmonella Enteritidis infection. To reach this aim, gene expression in the spleens of naive chickens and those intravenously infected with S.
Marta Matulova +7 more
doaj +1 more source
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Educational Items on Immunoglobulin genes.
Lefranc, MP, Huret, JL
openaire +3 more sources
BMC Biotechnology, 2011 Background Molecular cloning of functional immunoglobulin genes from single plasma cells is one of the most promising technologies for the rapid development of monoclonal antibody drugs. However, the proper insertion of PCR-amplified immunoglobulin genes
Isobe Masaharu +2 more
doaj +1 more source
CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation [PDF]
, 2017 In germinal centres (GC) mature B cells undergo intense proliferation and immunoglobulin gene modification before they differentiate into memory B cells or long-lived plasma cells (PC).
Galjart, Niels +5 more
core +5 more sources
Somatic hypermutation of immunoglobulin and non–immunoglobulin genes [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001 Somatic hypermutation (SHM) of immunoglobulin (Ig) genes is a highly specific mechanism restricted to B lymphocytes during only a few cell generations. Data presented here suggest that transcription of the target genes is required, but not sufficient for SHM.
U, Storb, H M, Shen, N, Michael, N, Kim
openaire +2 more sources
Physical map and one-megabase sequencing of the human immunoglobulin lambda locus
Genetics and Molecular Biology, 1998 The human immunoglobulin lambda (IGL) locus is located on chromosome 22q11.1-q11.2 and contains the genes responsible for the immunoglobulin lambda light chains. This locus was recently mapped (physical map) and its 1-Mb DNA totally sequenced.
Geraldo A.S. Passos Jr.
doaj +1 more source
Expansion of the preimmune antibody repertoire by junctional diversity in Bos taurus. [PDF]
PLoS ONE, 2014 Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative ...
Jenni Liljavirta +4 more
doaj +1 more source
Expression of immunoglobulin constant domain genes in neurons of the mouse central nervous system
Life Science Alliance, 2021 In this study, Scheurer et al demonstrate that two genes encoding the effector domain of immunoglobulins are not only expressed by lymphocytes of the immune system but also by neurons in the central nervous system.
Louis Scheurer +6 more
doaj +1 more source