Promoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasia. [PDF]
Li RN, Li CY, Lee CH, Peng CY, Wu MT.
europepmc +1 more source
Abstract Background Several therapeutic targets for non–small cell lung carcinoma (NSCLC) rely on protein expression by immunohistochemistry (IHC). Most biomarkers are validated on formalin‐fixed, paraffin‐embedded (FFPE) tissue; however, cytologic specimens, including cell blocks (CBs), that are subject to preanalytical variables are increasingly used.
Saroja Devi Geetha +3 more
wiley +1 more source
Screening Strategies Among High‐Risk Populations for Anal Cancer (ACCESS Study) Protocol
Abstract Background: Anal cancer is a human papillomavirus (HPV)‐associated malignancy that disproportionately affects high‐risk populations, including people living with HIV, men who have sex with men, and women with a history of high‐grade lower genital tract neoplasia.
Raju Subbiah +20 more
wiley +1 more source
Characterization of p16-positive stromal cells in age-related cardiac disorders. [PDF]
Morimura T +3 more
europepmc +1 more source
Siblings in Flight: Unravelling Reproductive Barriers Between Two Butterfly Sister Species
Using an integrative approach, we combine genetic, genome synteny and cytogenetic analyses, Wolbachia screening and morphology to assess the evolutionary history of two butterfly sister species (Erebia palarica and Erebia meolans) and elucidate their potential reproductive barriers.
Laura Torrado‐Blanco +6 more
wiley +1 more source
Senescence Markers and Associated Transcriptomic Changes Are Expressed at Early Stages of Alzheimer's Neuropathology but Are Not Independently Related to Dementia. [PDF]
Vazquez-Villaseñor I +9 more
europepmc +1 more source
Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson +13 more
wiley +1 more source
Dioscin attenuates D‑galactose‑induced retinal pigment epithelium senescence and epithelial-mesenchymal transition via the TGF‑β2/PI3K/Akt/β‑catenin pathway. [PDF]
Ouyang Q +7 more
europepmc +1 more source
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny +23 more
wiley +1 more source
HMOX2-driven crosstalk between vascular aging and heart failure: A multimodal bioinformatics and explainable machine learning approach with experimental validation. [PDF]
Li J +7 more
europepmc +1 more source

