Results 211 to 220 of about 2,142,199 (296)

Novel Target for Pathogenic Leptospira Detection via Colorimetric Loop‐Mediated Isothermal Amplification (LAMP): Development, Validation, and Comparative Analysis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 21, November 2026.
A novel colorimetric LAMP assay targeting the org‐hp gene was developed for rapid Leptospira detection. The assay is performed in a simple water bath at 65°C for 90 min, and results can be interpreted by a color change visible to the naked eye. This method provides a sensitive, specific, and field‐adaptable diagnostic tool for use in resource‐limited ...
Peyman Ghoraishizadeh, Benjie Clemente, Kween Saimuang, Sakaorat Lertjuthaporn, Sukhonta limsampan, Patcharapan Suwannin, Mongkol Techakasikornpanich, Galayanee Doungchawee, Edilberto Manahan, Kulachart Jangpatarapongsa   +9 more
wiley   +1 more source

Extracellular Vesicles for Space Biomedical Research

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
Microgravity reshapes EV biogenesis and cargo selection, which brings new opportunities for longitudinal liquid‐biopsy readouts of stress and aging‐like trajectories, as well as the regenerative products in spaceflight research. ABSTRACT Extracellular vesicles (EVs) are regulated, information‐rich nanovesicles that reflect aspects of parent‐cell state,
Samantha Ali, Brian I. Molina Diaz, Pei Zhuang, Zachary Greenberg, Ye Zhang, Jeffrey Richards, Danny Carlos, Stefanie Countryman, Christiaan Leeuwenburgh, Luke P. Lee, Mei He   +10 more
wiley   +1 more source

Productive or Transforming? How Epithelial Compartmentalization of HPV DNA and E6/E7 Transcripts Shapes Cervical Screening Assay Performance

Journal of Medical Virology, Volume 98, Issue 11, November 2026.
ABSTRACT The human papillomavirus (HPV) life cycle is linked to epithelial cell differentiation, with viral genome amplification, E6/E7 transcription, and virion assembly spatially compartmentalized within the cervical epithelium. This organization is disrupted in transforming lesions.
Konstanze Schichl, John Doorbar
wiley   +1 more source

CD47 is a regulator in doxorubicin-induced cardiac aging in male mice. [PDF]

Physiol Rep
Yan A, Mai R, Cao T, Duan C, Liu S, Wang X.   +5 more
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, Volume 6, Issue 11, Page 473-489, November 2026.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Punicalagin alleviates senile osteoporosis by inhibiting the senescence of bone mesenchymal stem cells via NRF2/HO-1 pathway. [PDF]

Regen Ther
Wang Y, Qin Y, Wang T, Zhang W, Chen K, Geng D, Yan Z, Xu Y, Lv S.   +8 more
europepmc   +1 more source

Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models

MedComm, Volume 7, Issue 11, November 2026.
Multiple mechanisms including senescent cell accumulation, metabolic and endotoxin‐driven stimulation of immune and endothelial cells contribute to inflammaging, the chronic low‐grade inflammatory status underlying age‐related diseases. Blocking leptin signaling in experimental models of inflammaging blunts inflammation in a model‐specific manner while
Valeria Pellegrini, Rosalba La Grotta, Alessia Metallo, Francesca Carreras, Chiara Frigé, Giulia Matacchione, Angelica Giuliani, Jacopo Sabbatinelli, Fabiola Olivieri, Francesca Rispoli, Lorenzo Drago, Cesare Celeste Berra, Raffaele Marfella, Giuseppe Paolisso, Giuseppe Matarese, Claudio Procaccini, Ilaria Spatocco, Giorgia Mele, Paola de Candia, Antonio Ceriello, Francesco Prattichizzo   +20 more
wiley   +1 more source

Atherosclerosis: From Pathogenesis to Therapeutic Interventions

MedComm, Volume 7, Issue 11, November 2026.
The diagram outlines the core mechanisms driving atherosclerosis, including endothelial dysfunction, inflammatory responses, phenotypic switching of smooth muscle cells, and the gut–vascular axis. It also presents the corresponding therapeutic approaches now under development, such as gene therapies, immunotherapies, and nanotechnology platforms ...
Enge Zhou, Chenxi Zhan, Yuting Li, Yi Zeng, Renfei Luo, Xin Ouyang, Shixing Liu, Renqiang Yang, Nianlong Yan, Long Jiang   +9 more
wiley   +1 more source

<i>P16</i> DNA Methylation Coupled with Somatic Copy Number Variations in the Development of Gastric Carcinomas. [PDF]

Cancers (Basel)
Yang Z, Zhou J, Deng L, Qiao J, Gu L, Deng D.   +5 more
europepmc   +1 more source

Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges

MedComm, Volume 7, Issue 11, November 2026.
Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu, Guangming Tu, Chao Wang, Hongyan Zhao, Ziyi Wu, Wei Li, Li Chen, Bailin Niu   +7 more
wiley   +1 more source