Results 41 to 50 of about 47,345 (308)

t(2;13)(p16;q12) [PDF]

, 2008
Review on t(2;13)(p16;q12), with data on clinics, and the genes ...
Huret, JL, JL Huret
core   +1 more source

Estudo genético do gene p16 pela técnica de PCR-SSCP e expressão de proteína p16 em melanomas de mucosa oral e melanomas cutâneos Genetic analysis of p16 gene by PCR-SSCP technique and protein p16 expression in oral mucosa and skin melanomas

Anais Brasileiros de Dermatologia, 2006
FUNDAMENTOS: A deleção e mutação do gene CDKN2a que codifica um inibidor específico da ciclina dependente de quinase 4, a proteína p16, têm sido implicadas na tumorigênese do melanoma cutâneo. Entretanto, pouco se conhece sobre essas alterações genéticas
Ricardo Hsieh, Fabrício Bitu Sousa, Aline Firmiano, Fabio Daumas Nunes, Marina Helena Cury Gallottini de Magalhães, Mírian Nacagami Sotto   +5 more
doaj   +1 more source

Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice

Frontiers in Oncology, 2022
BackgroundA feasible method to detect somatic copy number deletion (SCND) of genes is still absent to date.MethodsInterstitial base-resolution deletion/fusion coordinates for CDKN2A were extracted from published articles and our whole genome sequencing ...
Yuan Tian, Jing Zhou, Juanli Qiao, Zhaojun Liu, Liankun Gu, Baozhen Zhang, Youyong Lu, Rui Xing, Dajun Deng   +8 more
doaj   +1 more source

FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.

, 2012
PMCID: PMC3312909This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Ahmad Waseem (155362), Emilios Gemenetzidis (176601), Adiam W. Bahta (176614), Nadir, A, Ayesha Nadir, Ahmad Waseem, Deeviyaben Patel (176603), Gemenetzidis Emilios, Iain L. Hutchison (155346), Bahta, AW, Ayesha Nadir (176609), Hutchison, IL, Nadir Ayesha, Teh, MT, Iain L Hutchison, Muy-Teck Teh, Teh, M-T, Rameez Tariq, Gemenetzidis, E, Adiam W Bahta, Teh Muy-Teck, Muy-Teck Teh (155335), Patel, D, Emilios Gemenetzidis, Patel Deeviyaben, Waseem Ahmad, Tariq, R, Waseem, A, Deeviyaben Patel, Rameez Tariq (176604), Tariq Rameez, Hutchison Iain L., Bahta Adiam W.   +32 more
core   +1 more source

Expression of p16 Within Myenteric Neurons of the Aged Colon: A Potential Marker of Declining Function

Frontiers in Neuroscience, 2021
Human colonic neuromuscular functions decline among the elderly. The aim was to explore the involvement of senescence. A preliminary PCR study looked for age-dependent differences in expression of CDKN1A (encoding the senescence-related p21 protein) and ...
Alexandra Palmer, Sarah Epton, Ellie Crawley, Marilisa Straface, Luke Gammon, Meghan M. Edgar, Yichen Xu, Shezan Elahi, Joanne Chin-Aleong, Joanne E. Martin, Joanne E. Martin, Cleo L. Bishop, Cleo L. Bishop, Charles H. Knowles, Charles H. Knowles, Gareth J. Sanger   +15 more
doaj   +1 more source

Genetic detection of bladder cancer by microsatellite analysis of p16, RB1 and p53 tumor suppressor genes

, 2001
Purpose: We investigated the incidence of genetic alterations in urine specimens from patients with bladder cancer. Materials and Methods: A total of 28 cytological urine specimens were assessed for microsatellite alternations, and 15 microsatellite ...
Kazanis, I., Sourvinos, G., Cranidis, A., Delakas, D., Spandidos, D.A.   +4 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

t(4;12)(p16;p13) [PDF]

, 2006
Review on t(4;12)(p16;p13), with data on clinics, and the genes ...
Huret, JL, JL Huret
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Alteration of p16 and p15 genes in human uterine tumours [PDF]

British Journal of Cancer, 1999
The roles of the p16 and p15 inhibitor of cyclin-dependent kinase tumour suppressor genes were examined in human uterine cervical and endometrial cancers. p16 mRNA, examined by reverse transcription polymerase chain reaction (RT-PCR), was significantly reduced in five of 19 (26%) cervical and four of 25 (16%) endometrial tumours.
Nakashima, R, Fujita, M, Enomoto, T, Haba, T, Yoshino, K, Wada, H, Kurachi, H, Sasaki, M, Wakasa, K, Inoue, M, Buzard, G, Murata, Y   +11 more
openaire   +2 more sources