Results 121 to 130 of about 40,097 (234)

Roles of histone lysine methylation in neurodevelopment and related disorders

Ibrain, Volume 12, Issue 2, Page 201-221, Summer 2026.
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen, Yi Zhang, Hong Zhang, Xiaoli Liang   +3 more
wiley   +1 more source

Gene Transfer into Retinoblastoma Cells

BioTechniques, 1999
Kai-Yin Chau, Santa J. Ono
openaire   +3 more sources

Multidisciplinary Strategies for Targeting Tumor Dormancy in Breast Cancer Therapeutics: Hallmarks, Mechanism, and Approaches

iMetaMed, Volume 2, Issue 2, June 2026.
Clinical phases and classification of breast tumor dormancy. Tumor dormancy is described as the period after treatment until residual tumor cells become detectable as relapsing disease in clinic. During the period of clinical tumor dormancy, tumor mass dormancy and cellular dormancy may coexist.
Shu Chen, Hui Chen, Vijaya Raghavan, Jing Huang, Jin Wang   +4 more
wiley   +1 more source

Integrated Molecular Docking and Gene Expression Analyses Suggest a Potential Interaction Between Diphtheria Toxin and Bcl‐2 in HT‐29 Colorectal Cancer Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This study explores the interaction between Diphtheria Toxin (DT) and Bcl‐2 in HT‐29 cells. Integrating molecular docking with gene expression analysis, we demonstrate DT's high‐affinity binding to Bcl‐2 and a significant downregulation of BCL2 mRNA. These findings suggest that DT modulates anti‐apoptotic pathways, influencing colorectal cancer cell ...
Elif Ercan, Tugba Yalcinkaya, Belkis Levent, Ahmet Carhan   +3 more
wiley   +1 more source

Post-translational modifications in retinoblastoma: mechanisms, immune regulation, and therapeutic opportunities. [PDF]

Front Immunol
Xu L, Wang B, Li W, Luo X, Wang L, Zheng Y.   +5 more
europepmc   +1 more source

IL-18 suppresses retinoblastoma growth while concomitantly inducing an inflammation-/stress-associated and immune-remodeling response. [PDF]

Cancer Cell Int
Chen Z, Luo W, Wei D, Wang Q, Gou Q, Cao J, Mai Q, Chen X, Cai X, Chen X, Zhang J.   +10 more
europepmc   +1 more source

Synergistic Interaction Between HPV‐16 E7 Oncoprotein and Severe Vitamin A Deficiency in Regulating Adaptive Immunity in a Preclinical Cervical Cancer Model

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Persistent infection with High‐Risk Human Papillomavirus (HR‐HPV), particularly HPV‐16, is the main driver of cervical intraepithelial neoplasia (CIN) and cervical cancer (CC). However, HR‐HPV infection alone is insufficient for malignant progression and nutritional cofactors such as Vitamin A deficiency, may influence cervical neoplasia ...
Armando Chávez‐Ríos, Celina López‐Ruiz, Ian A. García‐Aguirre, Rodolfo Ocadiz‐Delgado, Francisco Garcia‐Sierra, Rogelio Hernández‐Pando, Solangy Lizcano‐Meneses, Patricio Gariglio   +7 more
wiley   +1 more source

Screening for differentially expressed genes in retinoblastoma gene chips through the GEO database and validation in clinical settings. [PDF]

Int J Ophthalmol
Liu CY, Luo R, Liu H, Xie RY, Chai Y, Xu Y.   +5 more
europepmc   +1 more source

Sublineage‐Specific A45S Polymorphism Alters the Biological Function of the Human Papillomavirus 11 E7 Protein

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT The E7 oncoprotein of human papillomavirus (HPV) plays a crucial role in viral pathogenesis and replication. Although it is generally highly conserved across HPV genotypes, naturally occurring E7 variants can display functional differences that may affect viral persistence, oncogenic potential, and host cellular responses.
Zsolt Barnabás Éles, Leila Rahmani, Eszter Gyöngyösi, Krisztina Szarka, István Rebenku, György Veress, Tamás Major, József Kónya, Anita Szalmás   +8 more
wiley   +1 more source

Growth hormone-secreting adenoma with lack of retinoblastoma protein expression. [PDF]

JCEM Case Rep
Salvatori R, Gallia GL, Lucas CG.
europepmc   +1 more source