Results 61 to 70 of about 2,134,276 (240)

Sex, gender, and retinoblastoma: analysis of 4351 patients from 153 countries. [PDF]

, 2021
OBJECTIVE: To investigate in a large global sample of patients with retinoblastoma whether sex predilection exists for this childhood eye cancer.
Waddell, Keith, Munier, Francis L, Chantada, GL, Munier, F.L., Theophile, T, Bowman, Richard, Khetan, V., Kaliki, Swathi, Ademola-Popoola, Dupe S, Berry, J.L., Ji, X., Theophile, Tuyisabe, Burton, M, Kaliki, S., Kivelä, Tero T., Sherief, Sadik T, Burton, Matthew, Reddy, M. Ashwin, Ademola-Popoola, D.S., Berry, Jesse L., Sherief, Sadik T., Astbury, Nicholas J, Khetan, Vikas, Ji, Xunda, Zondervan, M, Bascaran, C., Reddy, M Ashwin, Stacey, A.W., Berry, Jesse L, Astbury, NJ, Reddy, M.A., Munier, Francis L., Ademola-Popoola, DS, Chantada, Guillermo L, Bowman, R, Waddell, K, Blum, Sharon, Allen Foster,, Kivelä, Tero T, Stacey, AW, Chantada, G.L., Sherief, ST, Sherief, S.T., Bascaran, C, Cassoux, Nathalie, Staffieri, S.E., Rojanaporn, Duangnate, Allen Foster, Hessissen, L, Fabian, I.D., Burton, M., Fabian, ID, Blum, S, Bascaran, Covadonga, Rojanaporn, D, Staffieri, Sandra E, Waddell, K., Foster, A., Blum, S., Zondervan, Marcia, Reddy, MA, Astbury, N.J., Hessissen, L., Luna-Fineman, Sandra, Ademola-Popoola, Dupe S., Ji, X, Luna-Fineman, S., Fabian, Ido Didi, Stacey, Andrew W., Luna-Fineman, S, Staffieri, SE, Global Retinoblastoma Study Group, Cassoux, N, Berry, JL, Munier, FL, Kaliki, S, Rojanaporn, D., Kivelä, T.T., Chantada, Guillermo L., Stacey, Andrew W, Cassoux, N., Hessissen, Laila, Staffieri, Sandra E., Bowman, R., Zondervan, M., Kivelä, TT, Khetan, V, Theophile, T., Astbury, Nicholas J., Global Retinoblastoma Study Grp, Francis L. Munier, Nathalie Cassoux, Dupe S. Ademola-Popoola, Vikas Khetan, Tuyisabe Theophile, null Allen Foster, Laila Hessissen, null null, Swathi Kaliki, Tero T. Kivelä, M. Ashwin Reddy, Sharon Blum, Covadonga Bascaran, Guillermo L. Chantada, Sandra E. Staffieri, Matthew Burton, Duangnate Rojanaporn, Xunda Ji, Ido Didi Fabian, Andrew W. Stacey, Richard Bowman, Sadik T. Sherief, Keith Waddell, Jesse L. Berry, Marcia Zondervan, Nicholas J. Astbury, Sandra Luna-Fineman   +116 more
core   +1 more source

Gene expression study in retinoblastoma patients with different anaplasias and lateralities

Scientific Reports
To investigate the differences in gene expression and functional enrichment associated with anaplasia and laterality in retinoblastoma patients. Two datasets were selected from the GEO database of the National Center for Biotechnology Information of the ...
Wan Li, Kangkang Xu, Fei Chen
doaj   +1 more source

Polymorphisms of CDKN1A gene and risk of retinoblastoma [PDF]

Carcinogenesis, 2013
Retinoblastoma (RB) is a malignant neoplasia that occurs mostly in children under 5 years. Recently, CDKN1A gene has been shown to be up-regulated in a context of loss of function of pRb. This gene encodes the p21 protein, which is the bona fide effector of p53. We hypothesized whether two putatively functional single nucleotide polymorphisms (SNPs) of
Ivna Néria Silva Ribamar, Carvalho, Adriana Helena de Oliveira, Reis, Pedro H, Cabello, Fernando Regla, Vargas   +3 more
openaire   +2 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Understanding retinoblastoma: epidemiology and genetics [PDF]

, 2018
Retinoblastoma is usually initiated by a random mutation of a gene in a retinal cell. It is important to try and recognise if the child has germline retinoblastoma, as this may affect both eyes of the child. Siblings and future children of the child with
Mandeep S Sagoo, Fabian, ID, Ido Didi Fabian, Sagoo, MS   +3 more
core  

Intravitreal melphalan for persistent retinoblastoma vitreous seeds

, 2022
A 7-month-old male presented with bilateral retinoblastoma, initially group E OD and group C OS (International Intraocular Retinoblastoma Classification).
Redondo-Villanueva, MJH, Mercado, GJV
core   +1 more source

Identification of Epigenetically Modified Hub Genes and Altered Pathways Associated With Retinoblastoma

Frontiers in Cell and Developmental Biology, 2022
Retinoblastoma (Rb) is the most common childhood malignancy initiated by biallelic mutation in RB1 gene and driven by various epigenetic events including DNA methylation and microRNA dysregulation.
Aditi Karmakar, Aditi Karmakar, Md. Maqsood Ahamad Khan, Nidhi Kumari, Nidhi Kumari, Nidhi Kumari, Nalini Devarajan, Senthil Kumar Ganesan, Senthil Kumar Ganesan, Senthil Kumar Ganesan   +9 more
doaj   +1 more source

Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma

Equine Veterinary Journal, EarlyView.
Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley   +1 more source

Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation

BMC Research Notes, 2011
Background Although many molecular regulators of adipogenesis have been identified a comprehensive catalogue of components is still missing. Recent studies showed that the retinoblastoma protein (pRb) was expressed in the cell cycle and late cellular ...
Hansen Jacob B, Bornstein Stefan R, Bogner-Strauss Juliane G, Prokesch Andreas, Fischer Maria, Jørgensen Claus, Krogsdam Anne-M, Hakim-Weber Robab, Madsen Lise, Kristiansen Karsten, Trajanoski Zlatko, Hackl Hubert   +11 more
doaj   +1 more source