Results 201 to 210 of about 252,546 (355)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Leaf transcriptome differences between diploid and tetraploid bahiagrass. [PDF]

Plant Genome
Podio M, Santoro DF, Colono CM, Ortiz JPA, Albertini E, Pessino SC.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Publisher Correction: Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness

Scientific Reports, 2021
Nasibeh Khayer, Maryam Jalessi, Amin Jahanbakhshi, Alireza Tabib khooei, Mehdi Mirzaie   +4 more
doaj   +1 more source

Decoding unchanged transcriptome of Alzheimer's disease reveals an NCAM1 mRNA switch as a potential biomarker. [PDF]

iScience
Li H, Liu S, Miao D, Chen L, Sun Y, Wang G, Zhu Z, Li X, Lu Q.   +8 more
europepmc   +1 more source

Switching on genes with GeneSwitch [PDF]

Genome Biology, 2001
openaire   +1 more source

Repetitive sequences in class-switch recombination regions of immunoglobulin heavy chain genes.

Cell, 1981
T. Kataoka, T. Miyata, T. Honjo
semanticscholar   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

High-dimensional switches and the modeling of cellular differentiation

, 2005
Many genes have been identified as driving cellular differentiation, but because of their complex interactions, the understanding of their collective behaviour requires mathematical modelling.
Demongeot, J, Cinquin, O
core  

Allelic Variation at tRNA Genes in Three Nematode Species Indicates Mutation Load Despite Strong Purifying Selection. [PDF]

Genome Biol Evol
Bell AD, Simonti C, Baños H, Wang L, Heitsch C, Lachance J, Paaby AB.   +6 more
europepmc   +1 more source