Associations between single nucleotide polymorphisms in cellular viral receptors and attachment factor-related genes and humoral immunity to rubella vaccination. [PDF]
PLoS ONE, 2014 Viral attachment and cell entry host factors are important for viral replication, pathogenesis, and the generation and sustenance of immune responses after infection and/or vaccination, and are plausible genetic regulators of vaccine-induced immunity ...
Iana H Haralambieva +6 more
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Reads Binning Improves the Assembly of Viral Genome Sequences From Metagenomic Samples
Frontiers in Microbiology, 2021 Metagenomes can be considered as mixtures of viral, bacterial, and other eukaryotic DNA sequences. Mining viral sequences from metagenomes could shed insight into virus–host relationships and expand viral databases.
Kai Song
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Divergent Traits and Ligand-Binding Properties of the Cytomegalovirus CD48 Gene Family
Viruses, 2020 The genesis of gene families by the capture of host genes and their subsequent duplication is a crucial process in the evolution of large DNA viruses. CD48 is a cell surface molecule that interacts via its N-terminal immunoglobulin (Ig) domain with the ...
Pablo Martínez-Vicente +3 more
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Interferon-induced genes of the expanded IFIT family show conserved antiviral activities in non-mammalian species. [PDF]
PLoS ONE, 2014 Interferon-induced proteins with tetratricopeptide repeats (IFITs) are involved in the protective response to viral infection, although the precise mechanism of IFITs for reducing viral proliferation is currently unknown.
Mónica Varela +8 more
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Non-viral Gene Therapy for Osteoarthritis [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Strategies for delivering nucleic acids into damaged and diseased tissues have been divided into two major areas: viral and non-viral gene therapy. In this mini-review article we discuss the application of gene therapy for the treatment of osteoarthritis (OA), one of the most common forms of arthritis.
Ilona Uzieliene +6 more
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Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach. [PDF]
PLoS Genetics, 2010 Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants.
Matteo Fumagalli +6 more
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BMC Genomics, 2011 Background Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) are related human tumor viruses that cause primary effusion lymphomas (PEL) and Burkitt's lymphomas (BL), respectively.
Dresang Lindsay R +11 more
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Identification of the Immediate-Early Genes of Cyprinid Herpesvirus 2
Viruses, 2020 Cyprinid herpesvirus 2 (CyHV-2), which infects goldfish and crucian carp causing high mortality, is an emerging viral pathogen worldwide. The genome of CyHV-2 is large and comprises double-stranded DNA, including several genes similar to cyprinid ...
Ruizhe Tang +4 more
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Frontiers in Immunology, 2019 The activation of innate immunity by viral nucleic acids present in the cytoplasm plays an essential role in controlling viral infection in both immune and non-immune cells.
Xin Xie +3 more
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Localization of Frog Virus 3 Conserved Viral Proteins 88R, 91R, and 94L
Viruses, 2019 The characterization of the function of conserved viral genes is central to developing a greater understanding of important aspects of viral replication or pathogenesis.
Emily Penny, Craig R. Brunetti
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