Results 31 to 40 of about 5,662,228 (148)

Gene Dosage and Gene Duplicability [PDF]

open access: yesGenetics, 2008
Abstract The evolutionary process leading to the fixation of newly duplicated genes is not well understood. It was recently proposed that the fixation of duplicate genes is frequently driven by positive selection for increased gene dosage (i.e., the gene dosage hypothesis), because haploinsufficient genes were reported to have more ...
Wenfeng, Qian, Jianzhi, Zhang
openaire   +2 more sources

Genetic basis for nitrate resistance in Desulfovibrio strains

open access: yesFrontiers in Microbiology, 2014
Nitrate is an inhibitor of sulfate-reducing bacteria (SRB). In petroleum production sites, amendments of nitrate and nitrite are used to prevent SRB production of sulfide that causes souring of oil wells.
Hannah eKorte   +19 more
doaj   +1 more source

Gene–Gene and Gene–Environment Interactions in Apolipoprotein L1 Gene-Associated Nephropathy [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2014
Molecular genetics have revolutionized the understanding of susceptibility to the broad spectrum of kidney diseases with light microscopic appearance of FSGS, particularly in populations with recent African ancestry. These disorders include idiopathic FSGS, HIV-associated nephropathy, severe lupus nephritis, sickle cell nephropathy, and the primary ...
Barry I, Freedman, Karl, Skorecki
openaire   +2 more sources

StORF-Reporter: finding genes between genes

open access: yesNucleic Acids Research, 2022
Abstract Large regions of prokaryotic genomes are currently without any annotation, in part due to well-established limitations of annotation tools. For example, it is routine for genes using alternative start codons to be misreported or completely omitted.
Nicholas J Dimonaco   +4 more
openaire   +4 more sources

tRNAscan-SE On-line: integrating search and context for analysis of transfer RNA genes

open access: yesNucleic Acids Res., 2016
High-throughput genome sequencing continues to grow the need for rapid, accurate genome annotation and tRNA genes constitute the largest family of essential, ever-present non-coding RNA genes. Newly developed tRNAscan-SE 2.0 has advanced the state-of-the-
T. Lowe, Patricia P. Chan
semanticscholar   +1 more source

An optogenetic toolbox for unbiased discovery of functionally connected cells in neural circuits

open access: yesNature Communications, 2017
Mechanisms of neural processing can only be understood by revealing patterns of connectivity among the cellular components of the circuit. Here the authors report a new genetic toolbox, ‘Optobow’, which enables simultaneous optogenetic activation of ...
Dominique Förster   +3 more
doaj   +1 more source

Investigación de dos casos complejos de relación biológica

open access: yesIatreia, 2010
Presentamos dos casos complejos de investigación de la relación biológica con un diagnóstico conclusivo. El primero corresponde al caso de una menor sin madre, con presunto padre fallecido y como referencias solo se disponía de la presunta abuela paterna
Diana de Aguirre   +5 more
doaj  

Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation

open access: yesFrontiers in Pharmacology
AimNimodipine has shown neuroprotective effects in several studies; however, the specific targets and mechanisms remain unclear. This study aims to explore the potential targets and mechanisms of nimodipine in the treatment of neurodegenerative diseases (
Shuang Zheng   +7 more
doaj   +1 more source

Retinotectal circuitry of larval zebrafish is adapted to detection and pursuit of prey

open access: yeseLife, 2020
Retinal axon projections form a map of the visual environment in the tectum. A zebrafish larva typically detects a prey object in its peripheral visual field.
Dominique Förster   +5 more
doaj   +1 more source

Loss of Calretinin in L5a impairs the formation of the barrel cortex leading to abnormal whisker-mediated behaviors

open access: yesMolecular Brain, 2021
The rodent whisker-barrel cortex system has been established as an ideal model for studying sensory information integration. The barrel cortex consists of barrel and septa columns that receive information input from the lemniscal and paralemniscal ...
Mingzhao Su   +6 more
doaj   +1 more source

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