Results 41 to 50 of about 5,662,228 (148)

Gene-Gene and Gene-Environment Interactions in Mild Hyperhomocysteinemia [PDF]

open access: yesPathophysiology of Haemostasis and Thrombosis, 2003
Mild/moderate hyperhomocysteinemia (HHcy), a highly prevalent condition, is independently associated with an increased risk of arterial and venous thromboembolic diseases. Early reports of the association of mild/moderate HHcy with juvenile venous thromboembolism have shown familiarity for HHcy in relatives of index cases with thrombosis.
Armando, D'Angelo   +2 more
openaire   +2 more sources

Comprehensive Characterization of Cancer Driver Genes and Mutations

open access: yesCell, 2018
Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to combine and optimize them on large datasets are few.
Matthew H. Bailey   +499 more
semanticscholar   +1 more source

T-Gene: improved target gene prediction [PDF]

open access: yesBioinformatics, 2019
Abstract Motivation Identifying the genes regulated by a given transcription factor (TF) (its ‘target genes’) is a key step in developing a comprehensive understanding of gene regulation. Previously, we developed a method (CisMapper) for predicting the target genes of a TF based solely on the ...
Timothy O’Connor   +3 more
openaire   +4 more sources

Estudio genético de la población afrodescendiente del departamento del Chocó con marcadores ligados al cromosoma X

open access: yesIatreia, 2010
Los marcadores genéticos tipo microsatélites del Cromosoma X (X-STR) han recibido creciente atención tan sólo en los últimos 10 años. Se ha demostrado su gran capacidad para aclarar casos complejos de parentesco, tales como abuela paterna - nieta ...
Juan José Builes   +6 more
doaj  

In vivo and in situ measurements of the digestive characteristics of sainfoin in comparison with lucerne fed to sheep as fresh forages at two growth stages and as hay

open access: yesAnimal, 2008
In vivo and in situ digestive characteristics of sainfoin (Onobrychis viciifolia L., a tannin-rich forage) and lucerne (Medicago sativa L., a tannin-free forage) were compared to evaluate the effects of condensed tannins (CT) and growth stage (vegetative
J Aufrère, M. Dudilieu, C. Poncet
doaj   +1 more source

A Clinical Evaluation of Cardiovascular Emergencies: A Comparison of Responses from ChatGPT, Emergency Physicians, and Cardiologists

open access: yesDiagnostics
Background: Artificial intelligence (AI) tools, like ChatGPT, are gaining attention for their potential in supporting clinical decisions. This study evaluates the performance of ChatGPT-4o in acute cardiological cases compared to cardiologists and ...
Muhammet Geneş, Bülent Deveci
doaj   +1 more source

Gene–gene and gene–environment interactions in ulcerative colitis [PDF]

open access: yesHuman Genetics, 2013
Genome-wide association studies (GWAS) have identified at least 133 ulcerative colitis (UC) associated loci. The role of genetic factors in clinical practice is not clearly defined. The relevance of genetic variants to disease pathogenesis is still uncertain because of not characterized gene-gene and gene-environment interactions.
Ming-Hsi, Wang   +7 more
openaire   +2 more sources

Reporte de caso: exclusión de paternidad

open access: yesIatreia, 2010
Actualmente las pruebas de paternidad son realizadas empleando marcadores microsatélites tipo STR´s con el objetivo de establecer probabilidades de exclusión del 99.99% de acuerdo a la Ley 721 de2001 ó excluir a un presunto padre de la paternidad; por ...
William Usaquen   +8 more
doaj  

Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters

open access: yeseLife, 2019
Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and ...
Nikolai Petkau   +4 more
doaj   +1 more source

Assessment of ChatGPT’s Compliance with ESC-Acute Coronary Syndrome Management Guidelines at 30-Day Intervals

open access: yesLife
Background: Despite ongoing advancements in healthcare, acute coronary syndromes (ACS) remain a leading cause of morbidity and mortality. The 2023 European Society of Cardiology (ESC) guidelines have introduced significant improvements in ACS management.
Muhammet Geneş, Murat Çelik
doaj   +1 more source

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