Results 21 to 30 of about 1,694,828 (235)

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits [PDF]

, 2002
We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of ...
Robin Lovell-Badge, De Vries, Geert, Auger, CJ, Lovell-Badge, R, Catherine J. Auger, Elka M. Scordalakes, Swain, A, Simerly, Richard B., Lovell-Badge, Robin, Richard B. Simerly, Amanda Swain, Arnold, Arthur P., Simerly, RB, Burgoyne, PS, Scordalakes, Elka M., Emilie F. Rissman, Geert J. De Vries, Liang-Yo Yang, Burgoyne, Paul S., Yang, Liang-Yo, Yang, L-Y, Rissman, EF, Rissman, Emilie F., Paul S. Burgoyne, De Vries, G, Arnold, AP, Arthur P. Arnold, Scordalakes, EM, Swain, Amanda, Auger, Catherine J.   +29 more
core   +1 more source

Cbx2, a Polycomb Group Gene, Is Required for Sry Gene Expression in Mice [PDF]

Endocrinology, 2012
Mice lacking the function of the polycomb group protein CBX2 (chromobox homolog 2; also known as M33) show defects in gonadal, adrenal, and splenic development. In particular, XY knockout (KO) mice develop ovaries but not testes, and the gonads are hypoplastic in both sexes.
Katoh-Fukui, Yuko, Miyabayashi, Kanako, Komatsu, Tomoko, Owaki. Akiko, Baba, Takashi, Shima, Yuichi, Kidokoro, Tomohide, Kanai, Yoshiakira, Schedl, Andreas, Wilhelm, Dagmar, Koopman, Peter, Okuno, Yasushi, Morohashi, Ken-ichirou   +12 more
openaire   +5 more sources

Sex determination in mythology and history [PDF]

, 2005
The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core   +1 more source

Molecular study of developmental sex disorders in children

Egyptian Journal of Medical Human Genetics, 2015
Background: Sex determination and differentiation in humans are processes that involve the interaction of several genes such as SRY, SOX9 genes which are important in the development of the male genital system.
Soheir S. AboElella, Maha A.M. Tawfik, Wafaa moustafa M. Abo El-fotoh   +2 more
doaj   +1 more source

The study of a hermaphroditic sheep caused by a mutation in the promoter of SRY gene

Veterinary and Animal Science, 2023
In mammals, sex-determining region Y (SRY) gene plays vital role as a transcription factor to regulate the expression of the genes contributing to development of male genitals.
Farid Heidari, Mohaddeseh Rahbaran, Asieh Mirzaei, Mehran Mozafari Tabatabaei, Sara Shokrpoor, Frouzandeh Mahjoubi, Mehdi Shams Ara, Vahid Akbarinejad, Faramarz Gharagozloo   +8 more
doaj   +1 more source

Duplication of SOX3 in an SRY-negative 46,XX male with prostatic utricle: case report and literature review

BMC Medical Genomics, 2022
Background 46,XX male disorders of sex development are rare. Approximately 80% of cases of testicular tissue differentiation may be due to translocation of SRY to the X chromosome or an autosome. SRY-negative 46,XX males show overexpression of pro-testis
Jiansheng Wei, Changrong Liu, Minyan Zhang, Shen Liu, Junjie Fu, Peng Lin   +5 more
doaj   +1 more source

Sex determination from dental pulp DNA among Egyptians

Egyptian Journal of Forensic Sciences, 2017
Background A great challenge arises when sex determination of human remains is needed, especially when only, bone fragments or isolated teeth are available; such as in mass disasters.
M. Kholief, S. El Shanawany, R. Gomaa
doaj   +1 more source

Regulation of multiple renin–angiotensin system genes by Sry [PDF]

Journal of Hypertension, 2010
We demonstrated that the Sry gene complex on the spontaneously hypertensive rat (SHR) Y chromosome is a candidate locus for hypertension that accounts for the SHR Y chromosome blood pressure effect. All rat strains examined to date share six Sry loci, and a seventh Sry locus (Sry3) appears to be unique to SHR male rats.
Amy, Milsted, Adam C, Underwood, Jeff, Dunmire, Helen L, DelPuerto, Almir S, Martins, Daniel L, Ely, Monte E, Turner   +6 more
openaire   +2 more sources

SRY-PCR.

, 2020
PCR-product of the 519 bp of the segment of the SRY-gene (left column in each section) confirmed the existence of the male specific Y sex chromosome in the examined case with hypospadias.
Ioannis Proios (8282550), Viviana Genualdo (646442), Kirsten Hülskötter (8282553), Julia Metzger (149151), Sina Reinartz (3144546), Ottmar Distl (102156), Angela Perucatti (646438), Jürgen Rehage (169433), Alessandra Iannuzzi (646440), Maike Heppelmann (3538487), Andreas Beineke (201418), Marina Braun (5845154)   +11 more
core   +1 more source

Sexual differentiation of the brain: investigating the role of Sry using animal models [PDF]

Recent findings have challenged the dogma that gonadal hormones are the sole factor mediating sexual differentiation of the mammalian brain, and have highlighted the importance of sex-linked genes in this process, either independently, or in combination ...
Kopsida, Eleni
core   +6 more sources