Results 21 to 30 of about 23,557 (205)
BMC Medical Genomics, 2022 Background 46,XX male disorders of sex development are rare. Approximately 80% of cases of testicular tissue differentiation may be due to translocation of SRY to the X chromosome or an autosome. SRY-negative 46,XX males show overexpression of pro-testis
Jiansheng Wei +5 more
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The study of a hermaphroditic sheep caused by a mutation in the promoter of SRY gene
Veterinary and Animal Science, 2023 In mammals, sex-determining region Y (SRY) gene plays vital role as a transcription factor to regulate the expression of the genes contributing to development of male genitals.
Farid Heidari +8 more
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Sex determination from dental pulp DNA among Egyptians
Egyptian Journal of Forensic Sciences, 2017 Background A great challenge arises when sex determination of human remains is needed, especially when only, bone fragments or isolated teeth are available; such as in mass disasters.
M. Kholief, S. El Shanawany, R. Gomaa
doaj +1 more source
Cloning and Characterization of Bovine Sry Gene
Nihon Chikusan Gakkaiho, 1995 哺乳類における性決定因子とは精巣決定因子(ヒトではTDF,動物ではTdy)であり,その本体はSRY/Sry遺伝子と考えられている.PCRで増幅したヒトSRY遺伝子の一部をプローブとしてウシのゲノムライブラリーをスクリーニングすることによりウシのSry遺伝子を含むクローンを得た.HincIIおよびBamHI部位に挟まれた2.8kbのDNA断片を検索し,進化的に保存されているHMG (High mobility group)ボックスを含めウシSry遺伝子の5'上流および3'下流の塩基配列を決定した.HMGボックスならびにその5'側上流および3'側下流領域のプライマーDNAを合成し,ホルスタイン,F1牛(ホルスタイン雌,和牛雄),ヒツジ,ヤギ,およびマウスの雌雄DNAを鋳型としてPCRを行なったところ ...
KATO, Yuko +4 more
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Brain Sexual Differentiation and Requirement of SRY: Why or Why Not?
Frontiers in Neuroscience, 2017 Brain sexual differentiation is orchestrated by precise coordination of sex steroid hormones. In some species, programming of select male brain regions is dependent upon aromatization of testosterone to estrogen.
Cheryl S. Rosenfeld +3 more
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Scientific Reports, 2022 The genetic background of feline disorders of sex development (DSDs) is poorly understood. We performed comprehensive cytogenetic, molecular, and histological studies of 17 cats with abnormal external genitalia, unusual behavior, or tricolor coats ...
Monika Stachowiak +12 more
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Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Formation and Function in Assisted Fertilization. [PDF]
PLoS Genetics, 2015 Spermatogenesis is a key developmental process allowing for a formation of a mature male gamete. During its final phase, spermiogenesis, haploid round spermatids undergo cellular differentiation into spermatozoa, which involves extensive restructuring of
Yasuhiro Yamauchi +3 more
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Copy number variations of five Y chromosome genes in donkeys [PDF]
Archives Animal Breeding, 2017 In mammals, the Y chromosome plays a pivotal role in male sex determination and is essential for normal sperm production. A number of studies were conducted on Y chromosome genes of various species and identified single-copy and multi-copy genes ...
H. Han +5 more
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PRESENCE OF THE SRY GENE IN TESTICULAR CELLS OF AN XX KALE WITH NEGATIVE SRY IN BLOOD CELLS [PDF]
Pediatric Research, 1995 Testis differentiation is under the control of a testis-determining factor borne by the Y chromosome. SRY, a gene cloned from the sex-determining region of the human Y chromosome, has been equated with the testis-determining factor. Between 80 and 90% of sex-reversed XX male individuals have an anomalous Y in X chromosome translocation during meiosis ...
A Dardis +4 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source