Results 21 to 30 of about 2,083,424 (186)
Molecular study of developmental sex disorders in children
Egyptian Journal of Medical Human Genetics, 2015 Background: Sex determination and differentiation in humans are processes that involve the interaction of several genes such as SRY, SOX9 genes which are important in the development of the male genital system.
Soheir S. AboElella +2 more
doaj +1 more source
BMC Medical Genomics, 2022 Background 46,XX male disorders of sex development are rare. Approximately 80% of cases of testicular tissue differentiation may be due to translocation of SRY to the X chromosome or an autosome. SRY-negative 46,XX males show overexpression of pro-testis
Jiansheng Wei +5 more
doaj +1 more source
Regulation of multiple renin–angiotensin system genes by Sry [PDF]
Journal of Hypertension, 2010 We demonstrated that the Sry gene complex on the spontaneously hypertensive rat (SHR) Y chromosome is a candidate locus for hypertension that accounts for the SHR Y chromosome blood pressure effect. All rat strains examined to date share six Sry loci, and a seventh Sry locus (Sry3) appears to be unique to SHR male rats.
Amy, Milsted +6 more
openaire +2 more sources
The study of a hermaphroditic sheep caused by a mutation in the promoter of SRY gene
Veterinary and Animal Science, 2023 In mammals, sex-determining region Y (SRY) gene plays vital role as a transcription factor to regulate the expression of the genes contributing to development of male genitals.
Farid Heidari +8 more
doaj +1 more source
Sex determination in mythology and history [PDF]
, 2005 The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core +1 more source
Sex determination from dental pulp DNA among Egyptians
Egyptian Journal of Forensic Sciences, 2017 Background A great challenge arises when sex determination of human remains is needed, especially when only, bone fragments or isolated teeth are available; such as in mass disasters.
M. Kholief, S. El Shanawany, R. Gomaa
doaj +1 more source
, 2020 PCR-product of the 519 bp of the segment of the SRY-gene (left column in each section) confirmed the existence of the male specific Y sex chromosome in the examined case with hypospadias.
Ioannis Proios (8282550) +11 more
core +1 more source
Cloning and Characterization of Bovine Sry Gene
Nihon Chikusan Gakkaiho, 1995 哺乳類における性決定因子とは精巣決定因子(ヒトではTDF,動物ではTdy)であり,その本体はSRY/Sry遺伝子と考えられている.PCRで増幅したヒトSRY遺伝子の一部をプローブとしてウシのゲノムライブラリーをスクリーニングすることによりウシのSry遺伝子を含むクローンを得た.HincIIおよびBamHI部位に挟まれた2.8kbのDNA断片を検索し,進化的に保存されているHMG (High mobility group)ボックスを含めウシSry遺伝子の5'上流および3'下流の塩基配列を決定した.HMGボックスならびにその5'側上流および3'側下流領域のプライマーDNAを合成し,ホルスタイン,F1牛(ホルスタイン雌,和牛雄),ヒツジ,ヤギ,およびマウスの雌雄DNAを鋳型としてPCRを行なったところ ...
KATO, Yuko +4 more
openaire +2 more sources
Brazilian Journal of Medical and Biological Research, 2005 The WT1 transcription factor regulates SRY expression during the initial steps of the sex determination process in humans, activating a gene cascade leading to testis differentiation.
E.B. Tagliarini +6 more
doaj +1 more source
Sexual differentiation of the brain: investigating the role of Sry using animal models [PDF]
Recent findings have challenged the dogma that gonadal hormones are the sole factor mediating sexual differentiation of the mammalian brain, and have highlighted the importance of sex-linked genes in this process, either independently, or in combination ...
Kopsida, Eleni
core +5 more sources