Gene expression and functional abnormalities in XX/Sry Leydig cells [PDF]
Scientific Reports, 2021 The SRY gene induces testis development even in XX individuals. However, XX/Sry testes fail to produce mature sperm, due to the absence of Y chromosome carrying genes essential for spermatogenesis.
Shogo Yanai +10 more
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Quantitative dissection of sexual dimorphism in mice through Y-linked gene knockouts and multivariate phenotyping [PDF]
Scientific ReportsSexual dimorphism (SDM) is regulated by sex chromosomes, yet the specific contribution of individual genes remains unclear. To address this, we conducted a comprehensive phenotyping analysis to investigate the roles of Y chromosome-linked genes in SDM ...
Nobuhiko Tanaka +6 more
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Oestrogen blocks the nuclear entry of SOX9 in the developing gonad of a marsupial mammal [PDF]
BMC Biology, 2010 Background Hormones are critical for early gonadal development in nonmammalian vertebrates, and oestrogen is required for normal ovarian development.
Pask Andrew J +4 more
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Amplification of Ultra-Trace DNA from Early Sheep Embryos Based on qPCR: Establishing a Gender Identification System [PDF]
BiologyThe ability to identify and control the sex of embryos holds significant commercial implications for livestock production. Due to the high costs and instability of detection methods, it is necessary to establish a time-saving, effective, simple, and ...
Peng Niu +7 more
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Current Issues in Molecular Biology, 2023 Head and neck squamous cell carcinoma (HNSCC) is the sixth leading cancer and the fifth cause of cancer-related deaths worldwide with a poor 5-year survival.
Tomasz Kolenda +11 more
doaj +1 more source
Dissociable effects of Sry and sex chromosome complement on activity, feeding and anxiety-related behaviours in mice. [PDF]
PLoS ONE, 2013 Whilst gonadal hormones can substantially influence sexual differentiation of the brain, recent findings have suggested that sex-linked genes may also directly influence neurodevelopment. Here we used the well-established murine 'four core genotype' (FCG)
Eleni Kopsida +4 more
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A Novel Missense Mutation 224G>T (R75M) in SRY Coding Region Interferes with Nuclear Import and Results in 46, XY Complete Gonadal Dysgenesis. [PDF]
PLoS ONE, 2016 SRY-mutation-caused sex reversal is a rare disease and mostly associated with a de novo mutation since the patients with defective SRY is infertile. There are many reports about SRY-mutation associated 46, XY ovarian disorder of sex development (DSD ...
Wufang Fan +8 more
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The evolutionary process of mammalian sex determination genes focusing on marsupial SRYs
BMC Evolutionary Biology, 2018 Background Maleness in mammals is genetically determined by the Y chromosome. On the Y chromosome SRY is known as the mammalian male-determining gene. Both placental mammals (Eutheria) and marsupial mammals (Metatheria) have SRY genes.
Yukako Katsura +4 more
doaj +1 more source
THE SRY GENE VARIATIONS AMONGST SELECTED MADURA CATTLE POPULATIONS
Jurnal Kedokteran Hewan, 2018 The aim of this study was to determine the diversity of the sex-determining region Y (SRY) gene in Madura cattle bulls that had specifically selected for the production of frozen semen.
Koko Wisnu Prihatin +2 more
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Sex determination in mythology and history [PDF]
, 2005 The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch, U
core +2 more sources