Results 31 to 40 of about 1,694,828 (235)
Cloning and Characterization of Bovine Sry Gene
Nihon Chikusan Gakkaiho, 1995 哺乳類における性決定因子とは精巣決定因子(ヒトではTDF,動物ではTdy)であり,その本体はSRY/Sry遺伝子と考えられている.PCRで増幅したヒトSRY遺伝子の一部をプローブとしてウシのゲノムライブラリーをスクリーニングすることによりウシのSry遺伝子を含むクローンを得た.HincIIおよびBamHI部位に挟まれた2.8kbのDNA断片を検索し,進化的に保存されているHMG (High mobility group)ボックスを含めウシSry遺伝子の5'上流および3'下流の塩基配列を決定した.HMGボックスならびにその5'側上流および3'側下流領域のプライマーDNAを合成し,ホルスタイン,F1牛(ホルスタイン雌,和牛雄),ヒツジ,ヤギ,およびマウスの雌雄DNAを鋳型としてPCRを行なったところ ...
KATO, Yuko +4 more
openaire +2 more sources
Analysis of Sry duplications on the Rattus norvegicus Y-chromosome [PDF]
, 2013 Background: Gene copy number variation plays a large role in the evolution of genomes. In Rattus norvegicus and other rodent species, the Y-chromosome has accumulated multiple copies of Sry loci.
Adam C Underwood +17 more
core +1 more source
Brain Sexual Differentiation and Requirement of SRY: Why or Why Not?
Frontiers in Neuroscience, 2017 Brain sexual differentiation is orchestrated by precise coordination of sex steroid hormones. In some species, programming of select male brain regions is dependent upon aromatization of testosterone to estrogen.
Cheryl S. Rosenfeld +3 more
doaj +1 more source
Scientific Reports, 2022 The genetic background of feline disorders of sex development (DSDs) is poorly understood. We performed comprehensive cytogenetic, molecular, and histological studies of 17 cats with abnormal external genitalia, unusual behavior, or tricolor coats ...
Monika Stachowiak +12 more
doaj +1 more source
Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Formation and Function in Assisted Fertilization. [PDF]
PLoS Genetics, 2015 Spermatogenesis is a key developmental process allowing for a formation of a mature male gamete. During its final phase, spermiogenesis, haploid round spermatids undergo cellular differentiation into spermatozoa, which involves extensive restructuring of
Yasuhiro Yamauchi +3 more
doaj +1 more source
Copy number variations of five Y chromosome genes in donkeys [PDF]
Archives Animal Breeding, 2017 In mammals, the Y chromosome plays a pivotal role in male sex determination and is essential for normal sperm production. A number of studies were conducted on Y chromosome genes of various species and identified single-copy and multi-copy genes ...
H. Han +5 more
doaj +1 more source
PRESENCE OF THE SRY GENE IN TESTICULAR CELLS OF AN XX KALE WITH NEGATIVE SRY IN BLOOD CELLS [PDF]
Pediatric Research, 1995 Testis differentiation is under the control of a testis-determining factor borne by the Y chromosome. SRY, a gene cloned from the sex-determining region of the human Y chromosome, has been equated with the testis-determining factor. Between 80 and 90% of sex-reversed XX male individuals have an anomalous Y in X chromosome translocation during meiosis ...
A Dardis +4 more
openaire +1 more source
, 2014 SRY alignment (see GenBank accession numbers in Sup. Table 1)
Mills, L. Scott +9 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Mixed gonadal dysgenesis in 45,X Turner syndrome with gene [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2015 Turner syndrome is the most common chromosomal disorder in girls. Various phenotypic features show depending upon karyotype from normal female through ambiguous genitalia to male.
Jae Yeop Jung +6 more
doaj +1 more source