Results 51 to 60 of about 1,694,828 (235)

Cartographie fine de la région du gène PIS de la chèvre

INRAE Productions Animales, 2020
Chez les Mammifères, la différenciation sexuelle résulte d’une cascade complexe dont le premier acteur est le gène SRY, porté par le chromosome Y, qui masculinise la gonade indifférenciée.
E.P. CRIBIU, L. SCHIBLER, D. VAIMAN
doaj   +1 more source

Detection and Analysis of 12 Suspected Amelogenin Allelic Loss Cases [PDF]

Fayixue Zazhi, 2018
Objective To observe and analyse the Amelogenin allelic loss in parent-child identification cases, and to explore the type and mechanism of Amelogenin allelic loss as well as its influence on gender identification and solutions.
BI Jie, CHANG Jing-jing, YU Chun-ying
doaj   +1 more source

PRESENCE OF THE SRY GENE IN DISORDERS OF SEXUAL DIFFERENTIATION [PDF]

Pediatric Research, 1993
Identification of Y chromosomal material is important in individuals wilh disorders of sexual differentiation because 1) an increased risk for gonadal neoplasms exists and 2) insight into the process of sexual differentiation may be augmented. To better understand the role of SRY in disorders of sexual differentiation, tissues from 4 individuals were ...
M Kocova, S F Siegel, W A Rudert, M Trucco   +3 more
openaire   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

SRY and DAX1 in mammalian sex determination [PDF]

, 2003
Mammalian sex determination in its simplest form can be considered as a cell fate decision, dependent on SRY/Sry, the testis determining gene. SRY, a member of the HMG box family of transcription factors, is expressed in the indifferent XY gonad at ...
Canning, Claire Ann
core   +1 more source

Steroidogenic factor-1 (SF-1) gene mutation as a frequent cause of primary amenorrhea in 46,XY female adolescents with low testosterone concentration

Reproductive Biology and Endocrinology, 2010
Background Primary amenorrhea due to 46,XY disorders of sex differentiation (DSD) is a frequent reason for consultation in endocrine and gynecology clinics.
Servant Nadège, Raingeard Isabelle, Lespinasse James, Frances Anne-Marie, Polak Michel, Thibaud Elisabeth, Zenaty Delphine, Leprieur Elodie, Philibert Pascal, Audran Françoise, Paris Françoise, Sultan Charles   +11 more
doaj   +1 more source

Differentially expressed genes in the testes from early to mature development of banana shrimp (Fenneropenaeus merguiensis).

PLoS ONE, 2023
Banana shrimp (Fenneropenaeus merguiensis) is an economically important species in Thailand owing to the high value of globally exported frozen brine shrimps. However, the regulatory mechanisms governing spermatogenesis and testicular development in this
Uraipan Saetan, Wilaiwan Chotigeat
doaj   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Specificity of Key Sex Determination Genes in a Mammal with Ovotestes: The European Mole Talpa europaea

Animals
Here, for the first time, the structure of genes involved in sex determination in mammals (full Sry and partial Rspo1, Eif2s3x, and Eif2s3y) was analyzed for the European mole Talpa europaea with ovotestes in females.
Alexey Bogdanov, Maria Sokolova, Irina Bakloushinskaya   +2 more
doaj   +1 more source