Results 71 to 80 of about 1,694,828 (235)
, 2012 Functional gene categories for SRY and SOX9 direct binding target genes, number of representative genes per functional category listed are indicated.
Md. M. Haque (136011) +2 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta +26 more
wiley +1 more source
PCR amplification of SRY-related gene sequences reveals evolutionary conservation of the SRY-box motif. [PDF]
Genome Research, 1993 SRY (sex-determining region of the Y chromosome) has recently been identified as a key regulatory gene in mammalian sex determination. The open reading frame of this gene contains an 80-amino-acid motif, the SRY-box, which shares a high degree of homology with a DNA-binding domain found in the high-mobility-group (HMG) proteins HMG1 and HMG2.
A M, Coriat +4 more
openaire +2 more sources
, 2011 Cloning by the process of somatic cell nuclear transfer (SCNT) has been achieved in a variety of mammalian species and has many promising applications.
I. S. Hwang +8 more
core +1 more source
A rainbow trout SRY‐type gene expressed in pituitary glands
FEBS Letters, 1995 A Sox (SRY‐type HMG box) gene, designated SoxP1, was isolated from a cDNA library made from pituitaries of immature rainbow trout. Sequence analysis indicated that the cDNA had an open reading frame encoding 467 amino acid residues containing a DNA binding motif, known as the high mobility group (HMG) box. Northern blot analysis showed trout SoxP1 mRNA
Ito, Michihiko +4 more
openaire +2 more sources
Prenatal Diagnosis of 45,X/46,XX Mosaicism with Presence of SRY Gene. A Case Report
Medisur, 2013 The most common karyotype of the Turner syndrome is 45,X, although it may occur as mosaic 45,X/46,XX. In the Provincial Medical Genetics Center, a 42-year-old pregnant woman underwent an amniocentesis which led to the detection of mosaic Turner Syndrome (
Pedro Alí Díaz-Véliz Jiménez +3 more
doaj +2 more sources
Regulação da região promotora de genes do sistema renina-angiotensina pelas proteínas SRY e SOX3 [PDF]
, 2015 The renin-angiotensin system (RAS) is subject to sex-specific modulation by hormones and gene products. However, sex-differences in the balance between the vasoconstrictor/proliferative ACE (angiotensin-converting enzyme)/Ang II (angiotensin II)/AGTR1 ...
Fabiano Conde Araujo
core +1 more source
Oestrogen blocks the nuclear entry of SOX9 in the developing gonad of a marsupial mammal
BMC Biology, 2010 Background Hormones are critical for early gonadal development in nonmammalian vertebrates, and oestrogen is required for normal ovarian development.
Pask Andrew J +4 more
doaj +1 more source
An An accurate molecular method to sex elephants using PCR amplification of Amelogenin gene
Pachyderm, 2020 The use of molecular methods to identify the sex of elephants from non-invasive samples is essential for studies of population dynamics and population genetics.
George Lohay
doaj +1 more source
Developmental and Behavioral Effects of Arsenobetaine in Zebrafish (Danio rerio)
Journal of Applied Toxicology, EarlyView.ABSTRACT Arsenobetaine (AsB) is a prevalent organoarsenical in aquatic environments and is generally regarded as nontoxic. Despite its widespread occurrence, the developmental and neurobehavioral toxicity of AsB has not been systematically investigated.
Sravan Kumar Putnala +8 more
wiley +1 more source