Results 11 to 20 of about 5,981,041 (371)
Protein Science, 2022 My interest in the biological sciences began during my third year of graduate school at Caltech. I had just completed a detailed study of the thermal and photochemistry of 1,1-diazenes in the Dervan lab. However, rather than write my thesis, I decided to
P. Schultz
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Journal of Diabetes Research, 2021 Type 1 diabetes (T1D) is an autoimmune disease that culminates in beta cell destruction in the pancreas and, subsequently, deficiency in insulin production.
Tatiane M. Preisser +6 more
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Indirect Routes to Aminoacyl-tRNA: The Diversity of Prokaryotic Cysteine Encoding Systems
Frontiers in Genetics, 2022 Universally present aminoacyl-tRNA synthetases (aaRSs) stringently recognize their cognate tRNAs and acylate them with one of the proteinogenic amino acids.
Takahito Mukai +7 more
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A computational screen for alternative genetic codes in over 250,000 genomes
eLife, 2021 The genetic code has been proposed to be a ‘frozen accident,’ but the discovery of alternative genetic codes over the past four decades has shown that it can evolve to some degree.
Yekaterina Shulgina, Sean R Eddy
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A code within the genetic code: codon usage regulates co-translational protein folding
Cell Communication and Signaling, 2020 The genetic code is degenerate, and most amino acids are encoded by two to six synonymous codons. Codon usage bias, the preference for certain synonymous codons, is a universal feature of all genomes examined.
Yi Liu
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Resource conservation manifests in the genetic code
Science, 2020 Maximizing elements for your genome The accumulation of mutations is typically limited by selective parameters. One such parameter is the elements needed to build proteins and molecules to maintain cells.
Liat Shenhav, D. Zeevi
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Biophysical Interactions Underpin the Emergence of Information in the Genetic Code
Life, 2023 The genetic code conceals a ‘code within the codons’, which hints at biophysical interactions between amino acids and their cognate nucleotides. Yet, research over decades has failed to corroborate systematic biophysical interactions across the code ...
Aaron Halpern +6 more
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Special identity subgraph in genetic code [PDF]
Network Biology, 2022 The genetic code is a series of codons that stores genetic information about protein molecule formation. The identity graph of a group G is a graph in which the vertex set is the set of all elements of the group and two vertices in G are adjacent if a.b =
Birinchi Kumar Boruah, Tazid Ali
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Frontiers in Bioengineering and Biotechnology, 2022 Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of
Ragunathan Bava Ganesh +1 more
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Using Genetic Code Expansion for Protein Biochemical Studies
Frontiers in Bioengineering and Biotechnology, 2020 Protein identification has gone beyond simply using protein/peptide tags and labeling canonical amino acids. Genetic code expansion has allowed residue- or site-specific incorporation of non-canonical amino acids into proteins. By taking advantage of the
Christina Z. Chung +2 more
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