Results 11 to 20 of about 931,040 (332)

On the origin of the mitochondrial genetic code: Towards a unified mathematical framework for the management of genetic information [PDF]

open access: yes, 2012
The origin of the genetic code represents one of the most challenging problems in molecular evolution. The genetic code is an important universal feature of extant organisms and indicates a common ancestry of different forms of life on earth.
Diego Luis Gonzalez   +2 more
core   +2 more sources

Molecular analysis of cross-bacterial contamination detected in biotin-free buffers during diagnosis of HCV infections

open access: yesJournal of Applied Sciences and Environmental Management, 2005
In a routine work to determine Hepatitis C Virus (HCV) molecules in human infected serum with biotin/streptavidine enzyme linked immunosorbant assay (ELISA) technique, unexpected false positive was observed.
El-Rashdy M Redwan   +1 more
doaj   +1 more source

Biophysical Interactions Underpin the Emergence of Information in the Genetic Code

open access: yesLife, 2023
The genetic code conceals a ‘code within the codons’, which hints at biophysical interactions between amino acids and their cognate nucleotides. Yet, research over decades has failed to corroborate systematic biophysical interactions across the code ...
Aaron Halpern   +6 more
doaj   +1 more source

The genetic code [PDF]

open access: yesProceedings of the National Academy of Sciences, 2014
An excerpt from the pages of Marshall Nirenberg’s laboratory notebook from 1965. See Fig. S1 for complete image. Image courtesy of the National Library of Medicine.
openaire   +3 more sources

The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation

open access: yesCell Reports, 2023
Summary: Melanin is a pigment produced from the amino acid L-tyrosine in melanosomes. The CNC-family transcription factor Nrf3 is expressed in the basal layer of the epidermis, where melanocytes reside, but its melanogenic function is unclear.
Tsuyoshi Waku   +7 more
doaj  

New Genotypes of Sweetleaf (Stevia rebaudiana Bertoni) Acclimatized and Bred at Buzau

open access: yesBulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2019
In Romania, during the 1980s, this species was studied in addition to other sweetener plants, such as Jerusalem artichoke, sweet sorghum, sweet iris, etc. After 1996, the researches were restarted intensively at Vegetable Research and Development Station
Costel VÎNĂTORU   +3 more
doaj   +1 more source

Stops making sense: translational trade-offs and stop codon reassignment [PDF]

open access: yes, 2011
Background Efficient gene expression involves a trade-off between (i) premature termination of protein synthesis; and (ii) readthrough, where the ribosome fails to dissociate at the terminal stop. Sense codons that are similar in sequence to stop codons
A Eyre-Walker   +33 more
core   +4 more sources

NRF3 activates mTORC1 arginine-dependently for cancer cell viability

open access: yesiScience, 2023
Summary: Cancer cells coordinate the mTORC1 signals and the related metabolic pathways to robustly and rapidly grow in response to nutrient conditions. Although a CNC-family transcription factor NRF3 promotes cancer development, the biological relevance ...
Shuuhei Hirose   +13 more
doaj  

Detection of meta - and ortho -cleavage dioxygenases in bacterial phenol-degraders

open access: yesJournal of Applied Sciences and Environmental Management, 2006
In the last five years, in our lab, several bacterial genera capable of degrading phenol as sole carbon source were isolated from different Egyptian ecosystems. Phenol mineralization using these isolates was ranged from 55% to 0.4%.
Sahar Zaki
doaj   +1 more source

Codon Distribution in Error-Detecting Circular Codes

open access: yesLife, 2016
In 1957, Francis Crick et al. suggested an ingenious explanation for the process of frame maintenance. The idea was based on the notion of comma-free codes.
Elena Fimmel, Lutz Strüngmann
doaj   +1 more source

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