Results 51 to 60 of about 273,398 (272)
Marine nematode taxonomy in the DNA age: the present and future of molecular tools to access their biodiversity [PDF]
, 2010 Molecular taxonomy is one of the most promising yet challenging fields of biology. Molecular markers such as nuclear and mitochondrial genes are being used in a variety of studies surveying marine nematode taxa.
da Silva, Maria Cristina +7 more
core +2 more sources
Versatility of Synthetic tRNAs in Genetic Code Expansion [PDF]
Genes, 2018 Transfer RNA (tRNA) is a dynamic molecule used by all forms of life as a key component of the translation apparatus. Each tRNA is highly processed, structured, and modified, to accurately deliver amino acids to the ribosome for protein synthesis. The tRNA molecule is a critical component in synthetic biology methods for the synthesis of proteins ...
Kyle S. Hoffman +2 more
openaire +2 more sources
Viruses, 2022 Despite many efforts and diverse approaches, developing an effective herpesvirus vaccine remains a great challenge. Traditional inactivated and live-attenuated vaccines always raise efficacy or safety concerns. This study used Pseudorabies virus (PRV), a
Tong-Yun Wang +11 more
doaj +1 more source
eLife, 2021 Synthetic strategies for optically controlling gene expression may enable the precise spatiotemporal control of genes in any combination of cells that cannot be targeted with specific promoters.
Lloyd Davis +8 more
doaj +1 more source
Mitochondrial phylogeography and demographic history of the Vicuña: implications for conservation [PDF]
, 2007 The vicuña (Vicugna vicugna; Miller, 1924) is a conservation success story, having recovered from near extinction in the 1960s to current population levels estimated at 275 000.
A Prieto +60 more
core +1 more source
Convenient Genetic Encoding of Phenylalanine Derivatives through Their α-Keto Acid Precursors
Biomolecules, 2021 The activity and function of proteins can be improved by incorporation of non-canonical amino acids (ncAAs). To avoid the tedious synthesis of a large number of chiral phenylalanine derivatives, we synthesized the corresponding phenylpyruvic acid ...
Li Liu +8 more
doaj +1 more source
Site-specific incorporation of phosphotyrosine using an expanded genetic code. [PDF]
, 2017 Access to phosphoproteins with stoichiometric and site-specific phosphorylation status is key to understanding the role of protein phosphorylation.
Allison Wong +36 more
core +1 more source
A p-Adic Model of DNA Sequence and Genetic Code
, 2006 Using basic properties of p-adic numbers, we consider a simple new approach to describe main aspects of DNA sequence and genetic code. Central role in our investigation plays an ultrametric p-adic information space which basic elements are nucleotides ...
A. Khrennikov +15 more
core +1 more source
Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1
Nature Communications, 2023 The Ca2+ ion channel Orai1 is crucial in immune cells. Here, the authors applied genetic code expansion to transfer light-sensitivity to the Orai1 channel and achieved precise control over its function.
Lena Maltan +16 more
doaj +1 more source
Coevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic Life
Life, 2016 The origins of the components of genetic coding are examined in the present study. Genetic information arose from replicator induction by metabolite in accordance with the metabolic expansion law.
J. Tze-Fei Wong +4 more
doaj +1 more source