Results 1 to 10 of about 3,610,236 (181)

The genetic epidemiology of obsessive-compulsive disorder: a systematic review and meta-analysis. [PDF]

open access: yesTransl Psychiatry, 2023
The first systematic review and meta-analysis of obsessive-compulsive disorder (OCD) genetic epidemiology was published approximately 20 years ago. Considering the relevance of all the studies published since 2001, the current study aimed to update the ...
Blanco-Vieira T   +5 more
europepmc   +2 more sources

The human genetic epidemiology of COVID-19. [PDF]

open access: yesNat Rev Genet, 2022
Human genetics can inform the biology and epidemiology of coronavirus disease 2019 (COVID-19) by pinpointing causal mechanisms that explain why some individuals become more severely affected by the disease upon infection by the severe acute respiratory ...
Niemi MEK, Daly MJ, Ganna A.
europepmc   +2 more sources

Including diverse and admixed populations in genetic epidemiology research. [PDF]

open access: yesGenet Epidemiol, 2022
The inclusion of ancestrally diverse participants in genetic studies can lead to new discoveries and is important to ensure equitable health care benefit from research advances.
Caliebe A   +10 more
europepmc   +2 more sources

The Genetic Epidemiology of Joint Shape and the Development of Osteoarthritis. [PDF]

open access: yesCalcif Tissue Int, 2021
Congruent, low-friction relative movement between the articulating elements of a synovial joint is an essential pre-requisite for sustained, efficient, function.
Wilkinson JM, Zeggini E.
europepmc   +2 more sources

Genetic epidemiology [PDF]

open access: yesJournal of the Royal College of Physicians of Edinburgh, 2012
The field of genetic epidemiology has advanced considerably over the past decade. The falling costs of genome-wide association studies have allowed the identification of many common genetic variants associated with risk of illness. This has advanced the understanding of disease pathogenesis but has not led to widespread changes in care.
J K, Dunbar, H, Campbell
  +8 more sources

The PROMOTe study: targeting the gut microbiome with prebiotics to overcome age-related anabolic resistance: protocol for a double-blinded, randomised, placebo-controlled trial

open access: yesBMC Geriatrics, 2021
Background Loss of skeletal muscle mass and strength occurs with increasing age and is associated with loss of function, disability, and the development of sarcopenia and frailty.
Mary Ni Lochlainn   +11 more
doaj   +1 more source

Overcoming the Negligence in Laboratory Diagnosis of Mucosal Leishmaniasis

open access: yesPathogens, 2021
The northern region of Brazil, which has the largest number of cases of tegumentary leishmaniasis (TL) in the country, is also the region that has the highest diversity of species of vectors and Leishmania parasites.
Lilian Motta Cantanhêde   +9 more
doaj   +1 more source

Diverging destinies: ‘social’ data within the TwinsUK cohort [version 1; peer review: 2 approved]

open access: yesWellcome Open Research, 2022
Background: Twins offer social scientists a unique opportunity to understand the interplay of social factors and physical and mental well-being. TwinsUK is the largest UK registry of adult mono- and dy-zygotic twins, but most of the research that ...
Deborah Hart   +8 more
doaj   +1 more source

GENETIC EPIDEMIOLOGY [PDF]

open access: yesAnnual Review of Genetics, 1993
Every science has roots that antedate acceptance as a discipline. Neglecting these intimations, there is a consensus that population genetics became a recognised science about 1920, and that it split into two branches about 1960. One branch is concerned with historical processes, uniting genetics with anthropology and (in other species) with ...
openaire   +4 more sources

Prenatal diagnosis of Norrie disease after whole exome sequencing of an affected proband during an ongoing pregnancy: a case report

open access: yesBMC Medical Genetics, 2020
Background Hereditary ophthalmic pathology is a genetically heterogeneous group of diseases that occur either as an isolated eye disorder or as a symptom of hereditary syndromes (chromosomal or monogenic).
Andrey V. Marakhonov   +9 more
doaj   +1 more source

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