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The future of genetic epidemiology
Trends in Genetics, 1998 Genetic epidemiology is a hybrid discipline whose ultimate aim is to identify and to characterize population-level factors that contribute to disease. Genetic epidemiologists often pursue this aim through the design and implementation of studies that simultaneously invoke principles in population genetics, epidemiology, molecular biology and ...
Schork, N J, Cardon, L R, Xu, X
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Introduction to genetic epidemiology
Optometry - Journal of the American Optometric Association, 2011 Genetic epidemiology is of topical and increasingly practical relevance. The subject attempts to answer 2 questions: (1) is there a genetic component to a disease, and (2) what genes are involved? This article summarizes genetic epidemiologic methods, describing family- and population-based methods used to locate and identify genes and the advantages ...
Williams, M.A. +5 more
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Including diverse and admixed populations in genetic epidemiology research. [PDF]
Genet Epidemiol, 2022 The inclusion of ancestrally diverse participants in genetic studies can lead to new discoveries and is important to ensure equitable health care benefit from research advances.
Caliebe A +10 more
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Journal of the Royal College of Physicians of Edinburgh, 2012 The field of genetic epidemiology has advanced considerably over the past decade. The falling costs of genome-wide association studies have allowed the identification of many common genetic variants associated with risk of illness. This has advanced the understanding of disease pathogenesis but has not led to widespread changes in care.
J K, Dunbar, H, Campbell
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Annual Review of Genetics, 1993 Every science has roots that antedate acceptance as a discipline. Neglecting these intimations, there is a consensus that population genetics became a recognised science about 1920, and that it split into two branches about 1960. One branch is concerned with historical processes, uniting genetics with anthropology and (in other species) with ...
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Genetic Epidemiology of Psoriasis [PDF]
Current Dermatology Reports, 2014 Psoriasis is a chronic, inflammatory, immune-mediated skin condition with a prevalence of 0-11.8% across the world. It is associated with a number of cardiovascular, metabolic, and autoimmune disease co-morbidities. Psoriasis is a multifactorial disorder, influenced by both genetic and environmental factors.
Gupta, Rashmi +2 more
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Ecogeographic genetic epidemiology [PDF]
Genetic Epidemiology, 2008 AbstractComplex diseases such as cancer and heart disease result from interactions between an individual's genetics and environment, i.e. their human ecology. Rates of complex diseases have consistently demonstrated geographic patterns of incidence, or spatial “clusters” of increased incidence relative to the general population.
Chantel D, Sloan +6 more
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The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. [PDF]
, 2009 Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of visceral and cutaneous leishmaniasis, fatal and disfiguring diseases.
Fitpatrick, S. +15 more
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, 2020 Previous transcriptome-wide association studies (TWAS) have identified breast cancer risk genes by integrating data from expression quantitative loci and genome-wide association studies (GWAS), but analyses of breast cancer subtype-specific associations ...
Pasaniuc, Bogdan +9 more
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Role of genomic typing in taxonomy, evolutionary genetics, and microbial epidemiology. [PDF]
, 2001 Currently, genetic typing of microorganisms is widely used in several major fields of microbiological research. Taxonomy, research aimed at elucidation of evolutionary dynamics or phylogenetic relationships, population ...
Struelens, M. +18 more
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