Results 61 to 70 of about 2,745,050 (303)
I am hiQ—a novel pair of accuracy indices for imputed genotypes
BMC Bioinformatics, 2022 Background Imputation of untyped markers is a standard tool in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy with which genotypes are imputed is fundamental.
Albert Rosenberger +3 more
doaj +1 more source
Genetic Epidemiology of Epilepsy [PDF]
Epidemiologic Reviews, 1997 Epilepsy is one of the most common neurologic disorders, affecting approximately 4 percent of individuals at some time in their lives (1). An inherited contribution to its etiology has been suspected for centuries, yet until recently, little progress has been made in understanding the genetic influences on susceptibility.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
Gut microbiome composition and function reflect socioeconomic deprivation
npj Biofilms and MicrobiomesSocioeconomic status (SES) correlates with adverse health outcomes, but the underlying biological mechanisms remain unclear. We examined how area-level deprivation (Townsend Deprivation Index) influences gut microbiome composition and function and ...
Yu Lin +13 more
doaj +1 more source
The utility of DNA extracted from saliva for genome-wide molecular research platforms
BMC Research Notes, 2018 Objective The study aimed to investigate the suitability of DNA extracted from saliva for high throughput molecular genotyping and DNA methylation platforms by comparing its performance with that of DNA extracted from blood.
Fiona J. Bruinsma +4 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Genetic epidemiology: an expanding scientific discipline
, 1998 Genetic epidemiology is a relatively new discipline that studies the interaction between genetic and environmental factors in the etiology of human diseases.
Wyszynski Diego F., Diego F. Wyszynski
core +1 more source
Genetic epidemiology of eating disorders [PDF]
, 2016 We capture recent findings in the field of genetic epidemiology of eating disorders. As analytic techniques evolve for twin, population, and molecular genetics, new findings emerge at an accelerated pace.
Kleiman, Susan C. +5 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source