Results 91 to 100 of about 3,275,705 (300)
Does bounded rationality lead to individual heterogeneity? The impact of the experimentation process and of memory constraints [PDF]
In this paper we explore the effect of bounded rationality on the convergence of individual behavior toward equilibrium. In the context of a Cournot game with a unique and symmetric Nash equilibrium, firms are modeled as adaptive economic agents through ...
Marco Casari
core
Indian Journal of Ophthalmology, 2013 In this brief review we will discuss the reasoning and evolution of our current use of combined very high-fluence collagen crosslinking and laser in situ keratomileusis.
Anastasios John Kanellopoulos +1 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2016 Although compelling evidence suggests that the genetic etiology of complex diseases could be heterogeneous in subphenotype groups, little attention has been paid to phenotypic heterogeneity in genetic association analysis of complex diseases.
Yalu Wen, Lu, Q, Qing Lu, Wen, Y
core +1 more source
The theory and art of corneal cross-linking
Indian Journal of Ophthalmology, 2013 Before the discovery of corneal cross-linking (CXL), patients with keratoconus would have had to undergo corneal transplantation, or wear rigid gas permeable lenses (RGPs) that would temporarily flatten the cone, thereby improving the vision.
Rebecca McQuaid +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
AnimalsMustelids are a very diverse carnivoran group, boasting the largest number of carnivoran species today, with the most extreme ecological adaptations. Nevertheless, Neotropical Lyncodontini, one Neotropical mustelid subfamily, is one of the least studied ...
Manuel Ruiz-García +1 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Genetic heterogeneity of retinitis pigmentosa
, 2015 Genetic heterogeneity is a phenomenon in which a genetic disease can be transmitted by several modes of inheritance. The understanding of genetic heterogeneity is important in giving genetic counselling.The presence of genetic heterogeneity can be ...
Hartono, Hartono
core
Clinical relevance of genetic heterogeneity in HCV
Clinical relevance of genetic heterogeneity in ...
González-Candelas, F. +1 more
core +1 more source