Results 131 to 140 of about 2,328,313 (310)

Genetic Identification and Traceability of Insect Meals. [PDF]

Insects, 2023
Moulistanos A, Karaiskou N, Gkagkavouzis K, Minoudi S, Drosopoulou E, Ioannidou C, Panteli N, Zografou S, Karaouglanis D, Kotouzas D, Kontodimas D, Antonopoulou E, Triantafyllidis A.   +12 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Development of SSR markers and assessment of genetic diversity in native Nepenthes spp. in southern Thailand

Ornamental Horticulture
Nepenthes spp. (Nepenthaceae) is one of the popular genera of carnivorous plants, which has a special leaf modification with varying shapes, sizes, and shades of color.
Yaowaphan Sontikun, Benjamas Somwong, Duangkhaetita Kanjanasopa, Suraphon Thitithanakul, Potjamarn Suraninpong   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Update on the search of candidate genes for drought-tolerance in coffee [PDF]

, 2014
It is well known that drought periods affect coffee plant development, leading to plant death and abortion of developing fruits in case of severe drought.
Alves, Gabriel Sergio Costa, Andrade, Alan Carvalho, Aquino, Sinara O., Carneiro, Fernanda A, Costa, Tatiana S., Cotta, Michelle G., Duarte, Karoline Estefani, Marraccini, Pierre, Rego, Erica C.S.   +8 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk. [PDF]

, 2019
BackgroundThe development of an autistic brain is a highly complex process as evident from the involvement of various genetic and non-genetic factors in the etiology of the autism spectrum disorder (ASD). Despite being a multifactorial neurodevelopmental
Gu, Ran, Ji, Yu, Kumar, Santosh, Rai, Sunil, Reynolds, Kurt, Zhou, Chengji J   +5 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

High-Mountain Tuber Products Improve Selectively the Development and Detoxifying Capacity of Lactobacilli Strains as an Innovative Culture Strategy

Fermentation
The study provides valuable insights into the sustainable utilization of edible tuber peels from the high mountains of the Argentinian Puna, which constitutes promising reserves of bioactive phenolic compounds with the potential to enhance the ...
Cecilia Hebe Orphèe, María Inés Mercado, Fernando Eloy Argañaraz Martínez, Mario Eduardo Arena, Elena Cartagena   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source