Results 161 to 170 of about 2,328,313 (310)

The intervertebral discs' fibrocartilage as a DNA source for genetic identification in severely charred cadavers. [PDF]

Forensic Sci Med Pathol, 2022
Tomsia M, Droździok K, Banaszek P, Szczepański M, Pałasz A, Chełmecka E.   +5 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Morphological, acoustic and genetic identification of a reproducing population of the invasive African clawed frog Xenopuslaevis (Anura, Pipidae) recently discovered in Belgium. [PDF]

Zookeys, 2023
Pauwels OSG, Brecko J, Baeghe D, Venderickx J, Vanderheyden A, Backeljau T.   +5 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Genetic identification of Pid3-1 and its regulatory role in promoting blast resistance in rice. [PDF]

G3 (Bethesda)
Liu J, He N, Cheng Z, Lin S, Fu S, Wang M, Huang F, Abou-Elwafa SF, Al Aboud NM, Huang C, Yang D.   +10 more
europepmc   +1 more source

Mid-Infrared Photothermal-Fluorescence In Situ Hybridization for Functional Analysis and Genetic Identification of Single Cells. [PDF]

Anal Chem, 2023
Bai Y, Guo Z, Pereira FC, Wagner M, Cheng JX.   +4 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Genetic identification of mouse trigeminal afferents responsible for mechanical allodynia. [PDF]

Cell Rep
Li T, Son H, Arora V, Shannonhouse J, Kumari S, Chang D, Caterina M, Kim YS, Chung MK.   +8 more
europepmc   +1 more source

Genetic identification and reiterated captures suggest that the <i>Astyanax mexicanus</i> El Pachón cavefish population is closed and declining. [PDF]

Zool Res, 2023
Legendre L, Rode J, Germon I, Pavie M, Quiviger C, Policarpo M, Leclercq J, Père S, Fumey J, Hyacinthe C, Ornelas-García P, Espinasa L, Rétaux S, Casane D.   +13 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source