Results 21 to 30 of about 5,764,173 (258)

A novel approach to simulate gene-environment interactions in complex diseases [PDF]

, 2010
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with largest prevalence and mortality (cancer, heart disease, obesity, etc ...
Amato, Roberto, G. Raiconi, ROBERTO AMATO, Miele, Gennaro, Nicodemi Mario, D. D'Andrea, Amato Roberto, AND SERGIO COCOZZA, MARIO NICODEMI, MICHELE PINELLI, Nicodemi, Mario, D'Andrea Daniel, Pinelli, Michele, Sergio Cocozza, Raiconi, Giancarlo, GENNARO MIELE, Amato, R. (Roberto), Cocozza Sergio, Raiconi Giancarlo, Miele Gennaro, Giancarlo Raiconi, D’Andrea, Daniel, Cocozza, Sergio, Pinelli Michele, DANIEL D'ANDREA, D'Andrea, Daniel   +25 more
core   +1 more source

Learning Petri net models of non-linear gene interactions [PDF]

, 2005
Understanding how an individual's genetic make-up influences their risk of disease is a problem of paramount importance. Although machine-learning techniques are able to uncover the relationships between genotype and disease, the problem of automatically
Mayo, Michael
core   +1 more source

A survey of genetic improvement search spaces [PDF]

, 2019
Genetic Improvement (GI) uses automated search to improve existing software. Most GI work has focused on empirical studies that successfully apply GI to improve software's running time, fix bugs, add new features, etc. There has been little research into
Alexander, B, Petke, Justyna, Alexander, Brad, Petke, J, White, DR, Wagner, M., Barr, ET, White, David R, Wagner, M, Barr, Earl T, Alexander, B., White, D.R., Petke, J., Barr, E.T., Brownlee, AEI, Brownlee, Alexander E I, Wagner, Markus, Brownlee, A.E.I.   +17 more
core   +1 more source

Prediction of genetic interactions using machine learning and network properties

Frontiers in Bioengineering and Biotechnology, 2015
A genetic interaction is a type of interaction where the effect of one gene is modified by the effect of one or several other genes. These interactions are important for delineating functional relationships among genes and their corresponding proteins ...
Neel eMadhukar, Neel eMadhukar, Olivier eElemento, Gaurav ePandey   +3 more
doaj   +1 more source

The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated? [PDF]

, 2013
Interactions amongst genes, known as epistasis, are assumed to make a substantial contribution to the genetic variation in infectious disease susceptibility, but this claim is controversial.
Ebert, Dieter, Dieter Ebert, Hall, Matthew, Matthew D Hall, Hall, Matthew D.   +4 more
core   +1 more source

Effect of high salinity and of priming of non-germinated seeds by UV-C light on photosynthesis of lettuce plants grown in a controlled soilless system

Frontiers in Plant Science, 2023
High salinity results in a decrease in plant photosynthesis and crop productivity. The aim of the present study was to evaluate the effect of UV-C priming treatments of lettuce seeds on photosynthesis of plants grown at high salinity.
Salah Fgaier, Salah Fgaier, Jawad Aarrouf, Félicie Lopez-Lauri, Yves Lizzi, Florine Poiroux, Laurent Urban   +6 more
doaj   +1 more source

Genetic Alterations Impact Immune Microenvironment Interactions in Follicular Lymphoma. [PDF]

, 2020
Interactions between germinal center B cells and immune cells in the microenvironment can play integral roles in transformation and growth of follicular lymphoma (FL).
Ochsenbein, Adrian F., Riether, Carsten
core   +1 more source

Differential network biology

Molecular Systems Biology, 2012
Protein and genetic interaction maps can reveal the overall physical and functional landscape of a biological system. To date, these interaction maps have typically been generated under a single condition, even though biological systems undergo ...
Trey Ideker, Nevan J Krogan
doaj   +1 more source

How Variation in Risk Allele Output and Gene Interactions Shape the Genetic Architecture of Schizophrenia

, 2022
Schizophrenia is a highly heritable polygenic psychiatric disorder. Characterization of its genetic architecture may lead to a better understanding of the overall burden of risk variants and how they determine susceptibility to disease.
Merve Kasap, Kasap, Merve, Dwyer, Donard S., Donard S. Dwyer   +3 more
core   +1 more source

Beyond hybridization: the genetic impacts of non-reproductive ecological interactions of salmon aquaculture on wild populations [Elektronisk resurs]

, 2020
Cultured Atlantic salmon Salmo salar are of international socioeconomic value, and the process of domestication has resulted in significant behavioural, morphological, and allelic differences from wild populations.
Vasemägi, Anti,, Sveriges lantbruksuniversitet.   +1 more
core   +1 more source