Results 61 to 70 of about 5,764,173 (258)

mSphere of Influence: Comprehensive Genetic Analysis

mSphere, 2020
Jason M. Peters works in the fields of antibiotic resistance and biofuel production. In this mSphere of Influence article, he reflects on how the paper “A global genetic interaction network maps a wiring diagram of cellular function” by Costanzo et al ...
Jason M. Peters
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Precision nutrition targeting the gut microbiota for weight management: mechanisms and applications

Frontiers in Microbiology
The gut microbiota, a highly individualized microbial community, is increasingly recognized for its role in weight regulation and metabolic health. This narrative review examines the bidirectional associations between gut microbiota and weight management,
Liyuan Jin, Yuan Zhu, Yaozhe Ying, Pengcheng Yan, Huanzhi Jin, Zheyan Chen   +5 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

NOVEL APPROACH TO COMPOSITION OF BACTERIOPHAGE MIXTURES FOR ANTIBACTERIAL THERAPY

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Evaluate antibacterial activity of an experimental mixture of phages, belonging to several well-studied species. Materials and methods. The study was carried out using a group of 55 clinical Pseudomonas aeruginosa strains of various origins, 4 mono ...
E. A. Pleteneva, O. V. Shaburova, M. V. Burkaltseva, S. V. Krylov, A. M. Kaplan, E. N. Chesnokova, O. A. Polygach, N. N. Voroshilova, N. A. Mikhailova, V. V. Zverev, V. N. Krylov   +10 more
doaj  

Intricate MIB1-NOTCH-GATA6 Interactions in Cardiac Valvular and Septal Development

Journal of Cardiovascular Development and Disease
Genome-wide association studies and experimental mouse models implicate the MIB1 and GATA6 genes in congenital heart disease (CHD). Their close physical proximity and conserved synteny suggest that these two genes might be involved in analogous cardiac ...
Rebeca Piñeiro-Sabarís, Donal MacGrogan, José Luis de la Pompa   +2 more
doaj   +1 more source

Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo

Frontiers in Physiology, 2020
Arginyltransferase1 (ATE1) is a conserved enzyme in eukaryotes mediating posttranslational arginylation, the addition of an extra arginine to an existing protein.
David J. Wiley, Gennaro D’Urso, Fangliang Zhang, Fangliang Zhang   +3 more
doaj   +1 more source

Genetic Vectors Approach in a Study of Fine Structure of Interaction Between Risk Haplotype of HTR2A and HLA-DRB1 Shared Epitope Alleles in Rheumatoid Arthritis

, 2013
We introduce new quantitative characteristics of the population using an analogy to the system of multi-spin molecules: the disease fields, which may depend on interactions, and the susceptibility to disease as derivative of genetic vector's (GV's ...
Igor Sandalov, Leonid Padyukov, Sandalov, Igor,, Padyukov, L.   +3 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions

, 2016
The BioGRID database is an extensive repository of curated genetic and protein interactions for the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyces pombe, and the yeast Candida albicans SC5314, as well as for several other ...
Chatr-aryamontri, Andrew, Theesfeld, Chandra L., Boucher, Lorrie, Sellam, Adnane, Hirschman, Jodi, Dolinski, Kara, Heinicke, Sven, Livstone, Michael S., Kolas, Nadine, Breitkreutz, Ashton, Winter, Andrew, Nixon, Julie, Reguly, Teresa, Chang, Christie S., Breitkreutz, Bobby-Joe, Ramage, Lindsay, Stark, Chris, Chen, Daici, Tyers, Mike, Oughtred, Rose, O’Donnell, Lara, Rust, Jennifer M.   +21 more
core   +1 more source