Results 221 to 230 of about 1,985,505 (274)
Abstract Ethiopian durum wheat (Triticum turgidum ssp. durum) is a globally significant crop recognized for its rich genetic diversity, stress adaptation, and high grain quality. This review consolidates over 20 years of research on the phenotypic and genotypic characterization of Ethiopian durum wheat landraces, focusing on trait discovery, genome ...
Agegnehu Mekonnen Tessema +3 more
wiley +1 more source
A Guide for Exploring Pleiotropic Associations in Genome-Wide Association Studies Using Summary Statistics. [PDF]
Feng CY, Sugier PE, Zou N, Liquet B.
europepmc +1 more source
Shared genetic architecture between DTI‐ALPS traits and neurodegenerative diseases
Abstract INTRODUCTION Diffusion tensor image analysis along the perivascular space (DTI‐ALPS) index is associated with neurodegenerative diseases (NDDs), but its shared genetic basis with NDDs remains unclear. METHODS By integrating genome‐wide association datasets for three DTI‐ALPS traits and seven NDDs, we quantified polygenic overlap using MiXeR ...
Hong Zhou +10 more
wiley +1 more source
Multi-omics causal inference of childhood asthma triggered by ambient particulate matter. [PDF]
Li H, Ren X, Lei X, Li Y, Dong W.
europepmc +1 more source
Abstract INTRODUCTION Late‐onset Alzheimer's disease (LOAD) and major depressive disorder (MDD) share genetic etiologies. Here, we investigated brain transcriptomic landscapes to gain insights into shared and divergent molecular and biological etiologies across LOAD and MDD.
Michael W. Lutz +2 more
wiley +1 more source
Genetic evidence for the association between per- and polyfluoroalkyl substances exposure and rheumatoid arthritis risk: A Mendelian randomization study. [PDF]
Xu H, Liu J, Qiu X, He J, Sun W.
europepmc +1 more source
In a two‐step, two‐sample Mendelian randomization framework, genetically predicted higher weight was associated with higher odds of myasthenia gravis (MG; OR = 1.67), whereas higher glucose levels showed an inverse association with MG (OR = 0.50). Genetically predicted higher weight was also associated with higher glucose levels (β = 0.06), and the MR ...
Hai Lin +12 more
wiley +1 more source
The genetic association between celiac disease and risk of functional dyspepsia: A Mendelian randomization study. [PDF]
Tang J, Zhao R, Yuan Z, Li J, Cui X.
europepmc +1 more source
ABSTRACT Background Clear cell renal cell carcinoma (ccRCC) is hallmarked by profound metabolic reprogramming; however, its intricate crosstalk with the tumor immune microenvironment (TIME) and its clinical ramifications remain inadequately elucidated.
Yi Peng +4 more
wiley +1 more source
Unravelling the role of alanine in mental disorders: a Mendelian randomisation study. [PDF]
Huang X, Zhao JV.
europepmc +1 more source

