Results 231 to 240 of about 1,985,505 (274)

Mediators of the Association Between Stroke and Blood Cells: A Two‐Step Multivariable Mendelian Randomization Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This study investigated the association and causality between complete blood count (CBC) parameters and stroke in 6736 participants from the 2011–2016 NHANES. Key CBC indices were identified as independent stroke predictors, with some showing significant nonlinear correlations with stroke events.
Tao Chen, Yan Li, Long Cai, Yijun Liu, Pengchen Kuang, Liuyi Zou, Ping Li   +6 more
wiley   +1 more source

Targeting the GPR183/EBI2‒oxysterol axis in tuberculosis: Immunometabolic regulation and prospects for host‐directed therapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
GPR183/EBI2 links oxysterol metabolism with immune‐cell positioning and macrophage function in tuberculosis. The 7α,25‐OHC‐GPR183 axis regulates macrophage trafficking, autophagy and type I interferon responses. GPR183 represents a potential immunometabolic target for host‐directed therapy against tuberculosis..
Junfei Wang, Yingnan Zhou, Xunming Ji, Haiping Zhao, Lingjun Zhan   +4 more
wiley   +1 more source

Gene-level complexity explains genome-wide variation in the distribution of fitness effects. [PDF]

Mol Biol Evol
Yıldırım B, James JE.
europepmc   +1 more source

Triple Threat: Elucidating Evolution Under Antibiotic, Metal, and Phage Pressure in Escherichia coli

Ecology and Evolution, Volume 16, Issue 9, September 2026.
Antibiotic resistance threatens treatment of bacterial infections, increasing research into alternative therapies, in particular whether new resistances will arise to these novel treatments. We evolved bacteria under phage, antibiotic, and heavy metal exposure.
Lindsey W. McGee, Noah K. Radtke, Gretchen S. Taylor, Joseph L. Graves Jr., Liesl Jeffers‐Francis   +4 more
wiley   +1 more source

Comparing genome-wide significant and chemosensory variants as instruments for dietary patterns in Mendelian randomization. [PDF]

Int J Epidemiol
Hui PSC, Devlin BL, Evans DM, Hwang LD.
europepmc   +1 more source

Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Liu E, Sun F, Peng D, Xu W, Zou Q, Chen X, Wu X.   +6 more
europepmc   +1 more source

Viral infection and dementia risk: A systematic bidirectional Mendelian randomization analysis. [PDF]

Virus Res
Huang JW, Wang YF, Zheng WH, Cui QQ, Gao SQ, Guo Y.   +5 more
europepmc   +1 more source

Causal relationship between trace elements and pityriasis rosea: A Mendelian randomization analysis. [PDF]

Medicine (Baltimore)
Yu T, Mou X, Luo Y, Cao L, Chen P, Yu H, Yang C, Xu J.   +7 more
europepmc   +1 more source

Limited evidence for causal effects of circulating inflammatory cytokines on the risk of selected hematologic malignancies: a two-sample Mendelian randomization study. [PDF]

Blood Res
Zhang H, Zhang L, Zhao D, Ma B, Wang J, Liu X, Yin W, Shen Y, Yang L, Dong W, Wang C.   +10 more
europepmc   +1 more source

Causal relationship between asthma and hernia risk: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Lu Y, Yuan H, Li D, Yang G, Liu X, Wang X, Zhang K, Liu D.   +7 more
europepmc   +1 more source