Results 11 to 20 of about 1,352,174 (294)

The nk model and population genetics [PDF]

, 2005
The nk model of fitness interactions is examined. This model has been used by previous authors to investigate the effects of fitness epistasis on substitution dynamics in molecular evolution, and to make broader claims about the importance of epistasis ...
Barton, Barton, Bergman, Burch, Coyne, Edmands, Elena, Elena, Felsenstein, Fisher, Fitch, Fontana, Fraser, Gavrilets, Gillespie, Gillespie, Gillespie, Gillespie, Gumbel, Hansen, Hartl, Jeong, Kauffman, Kauffman, Kauffman, Kichler Holder, Kimura, Kimura, Kondrashov, Korona, Lenski, Macken, Mani, Maynard Smith, Moore, Ohta, Ohta, Ohta, Ohta, Orr, Orr, Orr, Peck, Perelson, Phillips, Provine, Schrag, Solow, Stephan, Tachida, Tachida, Weinberger, Welch, Whitlock, Zeng   +54 more
core   +2 more sources

Pedigree Analysis: A Team-Based Learning Activity

MedEdPORTAL, 2017
Introduction Regardless of their specialty, physicians, particularly those practicing primary care in rural areas, typically encounter genetic conditions.
Jack Thatcher, Patty Canfield, Laurie Bauer, Brian N. Griffith   +3 more
doaj   +1 more source

Chromosomal phase improves aneuploidy detection in non-invasive prenatal testing at low fetal DNA fractions

Scientific Reports, 2022
Non-invasive prenatal testing (NIPT) to detect fetal aneuploidy by sequencing the cell-free DNA (cfDNA) in maternal plasma is being broadly adopted. To detect fetal aneuploidies from maternal plasma, where fetal DNA is mixed with far-larger amounts of ...
Giulio Genovese, Curtis J. Mello, Po-Ru Loh, Robert E. Handsaker, Seva Kashin, Christopher W. Whelan, Lucy A. Bayer-Zwirello, Steven A. McCarroll   +7 more
doaj   +1 more source

The Pennsylvania grotto sculpin: population genetics [PDF]

Subterranean Biology, 2021
The Pennsylvania grotto sculpin is known from just two caves of the Nippenose Valley in central Pennsylvania, USA. They exhibit emergent troglobitic morphological traits and are the second northern-most cave adapted fish in the world.
Luis Espinasa, Drake M. Smith, Julianna M. Lindquist   +2 more
doaj   +3 more sources

In silico characterization of coding and non-coding SNPs of the androgen receptor gene

Informatics in Medicine Unlocked, 2021
The Androgen Receptor (AR), an important ligand-dependent nuclear transcription factor, encoded by the AR gene, functions in regulating the cell proliferation, migration, invasion, and apoptosis pathways. Single nucleotide polymorphisms (SNPs) of AR have
Maisha Adiba, Tonmoy Das, Anik Paul, Ashish Das, Sajib Chakraborty, Md Ismail Hosen, A.H.M. Nurun Nabi   +6 more
doaj   +1 more source

Growth, competition and cooperation in spatial population genetics [PDF]

, 2012
We study an individual based model describing competition in space between two different alleles. Although the model is similar in spirit to classic models of spatial population genetics such as the stepping stone model, here however space is continuous ...
Allstadt, Barton, Benzi, Berti, Birch, Cencini, Crow, D.R. Nelson, Doering, D’Ovidio, F. Toschi, Fisher, Frey, Gardiner, Hallatschek, Hernandez-Garcia, Kimura, Kimura, Kolmogorov, Korolev, Korolev, Korolev, Law, M.H. Jensen, Neufeld, Neuhauser, Odor, O’Malley, O’Malley, P. Perlekar, Perlekar, Perlekar, Pigolotti, Pringle, R. Benzi, Risken, S. Pigolotti, Smith, Tel, Vlad, Wright   +40 more
core   +3 more sources

Genetic selection strategies–population genetics

Poultry Science, 1997
This paper provides an overview of the association between population genetics and selection strategies in poultry. Relationships between artificial and natural selection and among causes contributing to limits to artificial selection are discussed.
P B, Siegel, E A, Dunnington
openaire   +2 more sources

The wild tomato species Solanum chilense shows variation in pathogen resistance between geographically distinct populations [PDF]

PeerJ, 2017
Wild tomatoes are a valuable source of disease resistance germplasm for tomato (Solanum lycopersicum) breeders. Many species are known to possess a certain degree of resistance against certain pathogens; however, evolution of resistance traits is yet ...
Remco Stam, Daniela Scheikl, Aurélien Tellier   +2 more
doaj   +2 more sources

Sampling related individuals within ponds biases estimates of population structure in a pond‐breeding amphibian

Ecology and Evolution, 2019
Effective conservation and management of pond‐breeding amphibians depends on the accurate estimation of population structure, demographic parameters, and the influence of landscape features on breeding‐site connectivity.
Kyle A. O'Connell, Kevin P. Mulder, Jose Maldonado, Kathleen L. Currie, Dennis M. Ferraro   +4 more
doaj   +1 more source

Reduction of a metapopulation genetic model to an effective one island model [PDF]

, 2018
We explore a model of metapopulation genetics which is based on a more ecologically motivated approach than is frequently used in population genetics. The size of the population is regulated by competition between individuals, rather than by artificially
Alan J. McKane, Crow J. F., César Parra-Rojas, Gardiner C. W., Hanski I., Pielou E. C., van Kampen N. G., Wiggins S., Wright S.   +8 more
core   +2 more sources