Results 1 to 10 of about 24,717 (147)
Genistein Targets STING-Driven Antiviral Responses
mBio, 2022 Cytoplasmic detection of DNA by cyclic GMP-AMP (cGAMP) synthase (cGAS) is an essential component of antiviral responses. Upon synthesis, cGAMP binds to the stimulator of interferon (IFN) genes (STING) in infected and adjacent cells through intercellular ...
Tomalika R. Ullah +9 more
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Aquaculture Reports, 2022 Genistein exhibits anti-diabetic and anti-lipogenic effects in mammals, however, there are rare reports on the effects of genistein on glucose and lipid metabolism in fish.
Liping Yang +8 more
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Frontiers in Cell and Developmental Biology, 2021 Genistein is a natural isoflavone with pharmacological or potentially anti-tumor properties. However, the resistance of cancer cells to genistein remains a major obstacle.
Tianyu Li +6 more
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Molecules, 2023 Previous studies have provided evidence that genistein exerts a therapeutic effect on different tumor cells. However, the mechanism of action of genistein against cervical cancer cells remains largely unknown. The aim of this study was to comprehensively
Tingting Chen +4 more
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The Role of Genistein in Mammalian Reproduction
Molecules, 2023 Genistein is a natural compound belonging to flavonoids, having antioxidant, anti-inflammatory, and anti-neoplastic properties. Genistein is considered a phytoestrogen.
Gabriella Guelfi +8 more
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Inhibition of castration-resistant prostate cancer growth by genistein through suppression of AKR1C3
Food & Nutrition Research, 2023 Background: Prostate cancer is the second leading cause of cancer-related death among males in America. The patients’ survival time is significantly reduced after prostate cancer develops into castration-resistant prostate cancer (CRPC).
Xiaoping Yu +6 more
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Frontiers in Nutrition, 2022 IntroductionInsulin signaling via the insulin receptor (IR) may be associated with the amelioration of diet-induced metabolic syndrome. Genistein, a soy isoflavone, has been suggested to play a role in the amelioration of high-fat diet-induced metabolic ...
Nana Zhang +6 more
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Nutrikinetic study of genistein metabolites in ovariectomized mice. [PDF]
PLoS ONE, 2017 This study was designed to evaluate the effect of ovariectomy on nutrikinetics of genistein metabolites. To characterize the time-dependent changes in genistein metabolite concentrations, we identified 13 genistein metabolites using ultra-performance ...
Da-Hye Lee +8 more
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Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein
Neural Regeneration Research, 2018 Genistein, a potent antioxidant compound, protects dopaminergic neurons in a mouse model of Parkinson's disease. However, the mechanism underlying this action remains unknown.
Huan-Cheng Wu +9 more
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Redox Report, 2022 Objective Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF ...
Yousra M. El-Far +4 more
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