Results 21 to 30 of about 31,152 (194)

Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS

Biochemistry Research International, 2017
Objective. To discuss the effects of genistein on the metabolism of celecoxib in vitro and in vivo. Method. In vitro, the effects of genistein on the metabolism of celecoxib were studied using rat and human liver microsomes.
Xiang Zheng, Jian Wen, Teng-hui Liu, Qiu-Geng Ou-yang, Jian-ping Cai, Hong-yu Zhou   +5 more
doaj   +1 more source

Genistein as a Potential Anticancer Agent against Ovarian Cancer

Journal of Traditional and Complementary Medicine, 2012
Genistein is known as the major component of isoflavone, which is present in high-soy diets. Genistein has received much attention because of its chemopreventive and therapeutic effects on various types of cancers.
Jung-Yun Lee, Hee Seung Kim, Yong-Sang Song, MD, PhD   +2 more
doaj   +1 more source

Genistein prevents bone loss in type 2 diabetic rats induced by streptozotocin

Food & Nutrition Research, 2020
Background: Diabetic osteoporosis has become a severe public health problem in the aging societies. Genistein has been reported to play an important role in preventing and treating metabolic diseases via its anti-inflammatory, antioxidant, anti ...
Rongrong Lu, Zicong Zheng, Yimin Yin, Zhuoqin Jiang   +3 more
doaj   +1 more source

Activation of Chloride Secretion by Isoflavone Genistein in Endometrial Epithelial Cells

Cellular Physiology and Biochemistry, 2013
Background /Aim: Genistein, the most active isoflavone found primarily in soybeans, alters ion transport functions in intestinal and airway epithelia.
Chatsri Deachapunya, Sutthasinee Poonyachoti   +1 more
doaj   +1 more source

A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN⁺) Product for Male Facial Skin: Effects on Skin Appearance and Properties. [PDF]

Skin Res Technol
ABSTRACT Background With increasing life expectancy, the aging population, particularly in Asia, is expanding rapidly. Combined with intense year‐round ultraviolet exposure, this accelerates skin aging. Male skin also exhibits distinct aging characteristics.
Na Takuathung M, Yaja K, Aisara J, Klinjan P, Anek P, Inpan R, Kantasa T, Chitphan J, Yeerong K, Teekachunhatean S, Koonrungsesomboon N.   +10 more
europepmc   +2 more sources

Biological evaluation of isoflavonoids from Genista halacsyi using estrogen-target cells: Activities of glucosides compared to aglycones.

PLoS ONE, 2019
The purpose of this study was to evaluate the response of estrogen target cells to a series of isoflavone glucosides and aglycones from Genista halacsyi Heldr.
Nikolas Fokialakis, Xanthippi Alexi, Nektarios Aligiannis, Athina Boulaka, Aggeliki K Meligova, George Lambrinidis, Eleftherios Kalpoutzakis, Harris Pratsinis, Antigoni Cheilari, Dimitra J Mitsiou, Sofia Mitakou, Michael N Alexis   +11 more
doaj   +1 more source

A highly selective cell-based fluorescent biosensor for genistein detection

Engineering Microbiology, 2023
Genistein, an isoflavone found mainly in legumes, has been shown to have numerous health benefits for humans. Therefore, there is substantial interest in producing it using microbial cell factories.
Lucy Fang-I Chao, Dany Liu, Verena Siewers   +2 more
doaj   +1 more source

Genistein Inhibits Human Colorectal Cancer Growth and Suppresses MiR-95, Akt and SGK1

Cellular Physiology and Biochemistry, 2015
Background: Genistein, a major isoflavonoid isolated from dietary soybean, has been shown to suppress the growth of several cancers through modulation of various pathways.
Jian Qin, Jia Xin Chen, Zhou Zhu, Jia An Teng   +3 more
doaj   +1 more source

Genistein alleviates colitis by suppressing inflammation and modulating colonic Marvinbryantia formatexigens abundance and metabolites

Current Research in Food Science
As an active ingredient of leguminous plants, genistein is extremely important for alleviating various human diseases. However, the regulatory effect of genistein on intestinal microbiota in alleviating enteritis is still unclear.
Yang He, Xiaoli Qin, Chaoyong Liao, Rafaela Lameira Souza Lima, Qihang Hou, Jiaqi Lei, Yujiao Lai, Qiuyu Jiang, Bo Wang, Bingkun Zhang   +9 more
doaj   +1 more source

Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G₂/M cell cycle arrest

BMC Cancer, 2006
Background New cancer therapeutic strategies must be investigated that enhance prostate cancer treatment while minimizing associated toxicities. We have previously shown that genistein, the major isoflavone found in soy, enhanced prostate cancer ...
Forman Jeffrey D, Kucuk Omer, Wang Yu, Raffoul Julian J, Sarkar Fazlul H, Hillman Gilda G   +5 more
doaj   +1 more source