Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers +3 more
wiley +1 more source
Determining variant effects with pooled prime editing. [PDF]
Kajba CM, Herger M.
europepmc +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
Draft genome sequence of <i>Staphylococcus aureus</i> N208 isolated from a nasal swab of a healthy female. [PDF]
Jablonska S +4 more
europepmc +1 more source
Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng +10 more
wiley +1 more source
Complete genome sequence of <i>Varibaculum</i> sp. GTC20041 isolated from a clinical specimen in Japan. [PDF]
Hayashi M +3 more
europepmc +1 more source
Unraveling the Inactivation Mechanisms of Human Adenovirus 2 in Sunlight Disinfection: Synergism between Direct and Indirect Pathways. [PDF]
Shin S, Lee Y, Kohn T.
europepmc +1 more source
Highly stable Cas9 promotes HBV genome destruction by antagonizing HSC70-mediated degradation. [PDF]
Li Z +8 more
europepmc +1 more source
Complete genome of Leuconostoc mesenteroides B22051 from Panax ginseng Meyer C. A. in South Korea. [PDF]
Jin GD, Kim HY, Kim EB, Lee B.
europepmc +1 more source
The rise of historical epigenomics and temporal analysis of gene regulation. [PDF]
Holleley CE, Hahn EE.
europepmc +1 more source

