Results 1 to 10 of about 70 (69)
Genome assemblies across the diverse evolutionary spectrum of Leishmania protozoan parasites [PDF]
Microbiology Resource Announcements, 2021 AbstractWe report high-quality draft assemblies and gene annotation for 13 species and/or strains of the protozoan parasite genera Leishmania, Endotrypanum and Crithidia, which span the phylogenetic diversity of the Leishmaniinae sub-family within the kinetoplastid order of the phylum Euglenazoa.
Fatima Silva-Franco +13 more
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Protozoan genomics for drug discovery [PDF]
Nature Biotechnology, 2005 Comparing the metabolic pathways of parasites and their hosts facilitates the identification of new drug targets.
David S. Roos, Kshitiz Chaudhary
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ProtozoaDB: dynamic visualization and exploration of protozoan genomes [PDF]
Nucleic Acids Research, 2007 ProtozoaDB (http://www.biowebdb.org/protozoadb) is being developed to initially host both genomics and post-genomics data from Plasmodium falciparum, Entamoeba histolytica, Trypanosoma brucei, T. cruzi and Leishmania major, but will hopefully host other protozoan species as more genomes are sequenced.
Margarita Ruiz +25 more
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Species diversity and genome evolution of the pathogenic protozoan parasite, Neospora caninum [PDF]
Infection, Genetics and Evolution, 2020 Neospora caninum is a cyst-forming coccidian parasite of veterinary and economical significance, affecting dairy and beef cattle industries on a global scale. Comparative studies suggest that N. caninum consists of a globally dispersed, diverse population of lineages, distinguished by their geographical origin, broad host range, and phenotypic features.
John Ellis, Larissa Calarco
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Genomic Databases and the Search of Protein Targets for Protozoan Parasites [PDF]
Current Drug Targets, 2009 The development of databases devoted to biological information opened the possibility to integrate, query and analyze biological data obtained from several sources that otherwise would be scattered through the web. Several issues arise in the handling of biological information, mainly due to the diversity of biological subject matter and the complexity
Luis Fernando Saraiva Macedo Timmers +6 more
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Molecular Ecology, EarlyView., 2023 Abstract Malaria is a mosquito‐borne disease caused by protozoans of the genus Plasmodium that affects both humans and wildlife. The fitness consequences of infections by avian malaria are well known in birds, however, little information exists on its impact on mosquitoes.
Marta Garrigós +4 more
wiley +1 more source
Restriction mapping of the genome of the protozoan parasite Theileria parva. [PDF]
Proceedings of the National Academy of Sciences, 1992 We have used a modified linking clone strategy and pulsed-field gel electrophoresis to derive a map of the 29 Sfi I and 4 Not I sites in the 10 million base pair genome of the protozoan parasite Theileria parva. This was achieved in the absence of classical genetic information. The map reveals four chromosomes.
Morzaria, S.P., Young, J.R.
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An Extremely Streamlined Macronuclear Genome in the Free-Living Protozoan Fabrea salina
Molecular Biology and Evolution, 2022 Abstract Ciliated protists are among the oldest unicellular organisms with a heterotrophic lifestyle and share a common ancestor with Plantae. Unlike any other eukaryotes, there are two distinct nuclei in ciliates with separate germline and somatic cell functions.
Bing Zhang +6 more
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Genomes and Genome Projects of Protozoan Parasites [PDF]
Current Issues in Molecular Biology, 2003 Protozoan parasites are causing some of the most devastating diseases world-wide. It has now been recognised that a major effort is needed to be able to control or eliminate these diseases. Genome projects for the most important protozoan parasites have been initiated in the hope that the read-out of these projects will help to understand the biology ...
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Status of protozoan genome analysis: trypanosomatids
Parasitology, 1999 The three trypanosomatid genome projects have employed common strategies which include: analysis of pulsed-field gel electrophoretic chromosomal karyotypes; physical mapping using big DNA (cosmid, pacmid P1, bacterial artificial chromosome, yeast artificial chromosome) libraries; partial cDNA sequence analysis to develop sets of expressed sequence ...
J. M. Blackwell, S. E. Melville
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