Results 31 to 40 of about 1,052,313 (231)
Genomic Databases and the Search of Protein Targets for Protozoan Parasites [PDF]
Current Drug Targets, 2009 The development of databases devoted to biological information opened the possibility to integrate, query and analyze biological data obtained from several sources that otherwise would be scattered through the web. Several issues arise in the handling of biological information, mainly due to the diversity of biological subject matter and the complexity
Luís Fernando S M, Timmers +6 more
openaire +2 more sources
A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes [PDF]
, 2014 Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological ...
Carlow, Clotilde K. S. +7 more
core +4 more sources
Mitochondrial genome maintenance—the kinetoplast story
FEMS Microbiology Reviews, 2022 Mitochondrial DNA replication is an essential process in most eukaryotes. Similar to the diversity in mitochondrial genome size and organization in the different eukaryotic supergroups, there is considerable diversity in the replication process of the ...
Simona Amodeo +2 more
semanticscholar +1 more source
Microorganisms, 2022 Scientists have discovered many ways to treat bacteria, viruses, and parasites in aquaculture; however, there is still an impossibility in finding a permanent solution for all types of diseases.
Md Akib Ferdous +6 more
semanticscholar +1 more source
A latent ability to persist: differentiation in Toxoplasma gondii [PDF]
, 2018 A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant stage (bradyzoite).
Jeffers, Victoria +3 more
core +1 more source
Comparative analyses of parasites with a comprehensive database of genome-scale metabolic models.
PLoS Computational Biology, 2022 Protozoan parasites cause diverse diseases with large global impacts. Research on the pathogenesis and biology of these organisms is limited by economic and experimental constraints.
Maureen A Carey +5 more
doaj +1 more source
Sunlight-mediated inactivation of health-relevant microorganisms in water: a review of mechanisms and modeling approaches. [PDF]
, 2018 Health-relevant microorganisms present in natural surface waters and engineered treatment systems that are exposed to sunlight can be inactivated by a complex set of interacting mechanisms.
Boehm, Alexandria +16 more
core +1 more source
A novel component of the mitochondrial genome segregation machinery in trypanosomes
Microbial Cell, 2016 We recently described a new component (TAC102) of the mitochondrial genome segregation machinery (mtGSM) in the protozoan parasite Trypanosoma brucei. T.
Anneliese Hoffmann +2 more
doaj +1 more source
Homologous Recombination in Protozoan Parasites and Recombinase Inhibitors
Frontiers in Microbiology, 2017 Homologous recombination (HR) is a DNA double-strand break (DSB) repair pathway that utilizes a homologous template to fully repair the damaged DNA. HR is critical to maintain genome stability and to ensure genetic diversity during meiosis. A specialized
Andrew A. Kelso +7 more
doaj +1 more source
Virulence, 2022 Protozoan predation has been demonstrated to be a strong driving force for bacterial defence strategies in the environment. Our previous study demonstrated that Aeromonas hydrophila NJ-35, which evolved small-colony variants (SCVs), displayed various ...
Yuhao Dong +8 more
doaj +1 more source