Results 11 to 20 of about 669,373 (262)
INVERTED REPEATS IN VIRAL GENOMES [PDF]
Fluctuation and Noise Letters, 2005 We investigate 738 complete genomes of viruses to detect the presence of short inverted repeats. The number of inverted repeats found is compared with the prediction obtained for a Bernoullian and for a Markovian control model. We find as a statistical regularity that the number of observed inverted repeats is often greater than the one expected in ...
Rosario N. Mantegna +3 more
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Genomics in Plant Viral Research
Viruses, 2022 Plant viruses constitute a large group of pathogens causing damaging diseases in many agricultural and horticultural crops around the world [...]
Solomon Maina, Brendan Rodoni
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Packing nanomechanics of viral genomes [PDF]
The European Physical Journal E, 2008 We investigate the osmotic equilibrium between a bulk polyethylene glycol (PEG) solution and DNA tightly packed in a spherical capsid. We base our analysis on the equations of thermodynamic equilibrium in terms of osmotic pressure. The equality between external osmotic pressure of PEG and osmotic pressure of tightly packed DNA gives us the DNA ...
V. A. Parsegian +4 more
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Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle? [PDF]
, 2013 DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely required for the expression of many viral genes.
Sinclair, Alison J
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Genomic Analysis of Viral Outbreaks [PDF]
Annual Review of Virology, 2016 Genomic analysis is a powerful tool for understanding viral disease outbreaks. Sequencing of viral samples is now easier and cheaper than ever before and can supplement epidemiological methods by providing nucleotide-level resolution of outbreak-causing pathogens.
Stephen F. Schaffner +4 more
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Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
, 2018 The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan +3 more
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Sherlock Genomes — viral investigator [PDF]
Nature Reviews Microbiology, 2013 This month's Genome Watch highlights how deep sequencing technologies have vastly reduced the time and prior knowledge needed to generate viral genomes.
Sarah E. Smith, Rachael S. Wash
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Assembly of viral genomes from metagenomes [PDF]
Frontiers in Microbiology, 2014 Viral infections remain a serious global health issue. Metagenomic approaches are increasingly used in the detection of novel viral pathogens but also to generate complete genomes of uncultivated viruses. In silico identification of complete viral genomes from sequence data would allow rapid phylogenetic characterization of these new viruses.
Saskia L Smits +11 more
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Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably? [PDF]
, 2004 During virus assembly, all retroviruses specifically encapsidate two copies of full-length viral genomic RNA in the form of a non-covalently linked RNA dimer.
Liang, Chen +2 more
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G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy [PDF]
, 2018 G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in ...
Richter, Sara N, Ruggiero, Emanuela
core +1 more source