Results 31 to 40 of about 776,538 (310)
Structure of the herpes-simplex virus portal-vertex [PDF]
, 2018 Herpesviruses include many important human pathogens such as herpes simplex virus, cytomegalovirus, varicella-zoster virus, and the oncogenic Epstein–Barr virus and Kaposi sarcoma–associated herpesvirus.
Bhella, David +3 more
core +2 more sources
Genomic Analysis of Viral Outbreaks [PDF]
Annual Review of Virology, 2016 Genomic analysis is a powerful tool for understanding viral disease outbreaks. Sequencing of viral samples is now easier and cheaper than ever before and can supplement epidemiological methods by providing nucleotide-level resolution of outbreak-causing pathogens.
Shirlee, Wohl +2 more
openaire +2 more sources
Telomeres and Viruses: Common Themes of Genome Maintenance
Frontiers in Oncology, 2012 Genome maintenance mechanisms actively suppress genetic instability associated with cancer and aging. Some viruses provoke genetic instability by subverting the host’s control of genome maintenance.
Zhong eDeng +2 more
doaj +1 more source
Genome editing technologies to fight infectious diseases [PDF]
, 2017 Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa +2 more
core +1 more source
Intracellular sensing of viral genomes and viral evasion [PDF]
Experimental & Molecular Medicine, 2019 AbstractDuring viral infection, virus-derived cytosolic nucleic acids are recognized by host intracellular specific sensors. The efficacy of this recognition system is crucial for triggering innate host defenses, which then stimulate more specific adaptive immune responses against the virus.
Hyun-Cheol Lee +2 more
openaire +3 more sources
Genomics in Plant Viral Research
Viruses, 2022 Plant viruses constitute a large group of pathogens causing damaging diseases in many agricultural and horticultural crops around the world [...]
Solomon Maina, Brendan Rodoni
openaire +3 more sources
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
Nature Communications, 2023 Dilated cardiomyopathy is the second most common cause for heart failure with no cure except a high-risk heart transplantation. Approximately 30% of patients harbor heritable mutations which are amenable to CRISPR-based gene therapy.
Markus Grosch +17 more
doaj +1 more source
Isolation, Characterization, and Differentiation Potential of Canine Adipose-Derived Stem Cells
Cell Transplantation, 2010 Adipose tissue may represent a potential source of adult stem cells for tissue engineering applications in veterinary medicine. It can be obtained in large quantities, under local anesthesia, and with minimal discomfort.
N. M. Vieira +5 more
doaj +1 more source
mSystems, 2022 Human cells identify invading pathogens and activate immune signaling pathways through a wide array of pattern recognition receptors, including DNA sensors.
Timothy R. Howard +3 more
doaj +1 more source
Allosteric HIV-1 integrase inhibitors lead to premature degradation of the viral RNA genome and integrase in target cells [PDF]
, 2017 Recent evidence indicates that inhibition of HIV-1 integrase (IN) binding to the viral RNA genome by allosteric integrase inhibitors (ALLINIs) or through mutations within IN yields aberrant particles in which the viral ribonucleoprotein complexes (vRNPs)
Elliott, Jennifer +8 more
core +2 more sources