Results 61 to 70 of about 2,398,369 (345)
Viral genome integration of canine papillomavirus 16
Papillomavirus Research, 2019 Papillomaviruses infect humans and animals, most often causing benign proliferations on skin or mucosal surfaces. Rarely, these infections persist and progress to cancer.
Jennifer Luff +5 more
doaj +1 more source
A new strategy for the treatment of viral infections [PDF]
, 2006 Intact viruses, containing no viral genome but which are loaded with a therapeutic drug or virus like particles loaded with antiviral drugs are potentially selective drug carriers for the intracellular delivery of therapeutics.
Wolf, Markus
core +1 more source
Genome-wide analysis of influenza viral RNA and nucleoprotein association
Nucleic Acids Research, 2017 Influenza A virus (IAV) genomes are composed of eight single-stranded RNA segments that are coated by viral nucleoprotein (NP) molecules. Classically, the interaction between NP and viral RNA (vRNA) is depicted as a uniform pattern of ‘beads on a string’.
Nara Lee +5 more
semanticscholar +1 more source
Microbiome, 2020 Viruses are central to microbial community structure in all environments. The ability to generate large metagenomic assemblies of mixed microbial and viral sequences provides the opportunity to tease apart complex microbiome dynamics, but these analyses ...
Kristopher Kieft +2 more
semanticscholar +1 more source
Structure of the herpes-simplex virus portal-vertex [PDF]
, 2018 Herpesviruses include many important human pathogens such as herpes simplex virus, cytomegalovirus, varicella-zoster virus, and the oncogenic Epstein–Barr virus and Kaposi sarcoma–associated herpesvirus.
Bhella, David +3 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance An unresolved issue of SARS-CoV-2 disease is that patients often remain positive for viral RNA as detected by PCR many weeks after the initial infection in the absence of evidence for viral replication.
Liguo Zhang +5 more
semanticscholar +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
High-throughput screening of human genetic variants by pooled prime editing
Cell GenomicsSummary: Multiplexed assays of variant effect (MAVEs) enable scalable functional assessment of human genetic variants. However, established MAVEs are limited by exogenous expression of variants or constraints of genome editing.
Michael Herger +5 more
doaj +1 more source
Functional RNA Elements in the Dengue Virus Genome
Viruses, 2011 Dengue virus (DENV) genome amplification is a process that involves the viral RNA, cellular and viral proteins, and a complex architecture of cellular membranes.
Andrea V. Gamarnik +2 more
doaj +1 more source
Viruses, 2021 HIV persists via integration of the viral DNA into the human genome. The HIV DNA pool within an infected individual is a complex population that comprises both intact and defective viral genomes, each with a distinct integration site, in addition to a ...
Guinevere Q. Lee
doaj +1 more source