Results 31 to 40 of about 22,469,227 (260)

Genome-wide association studies in psychiatry: Current perspectives

open access: yesEuropean Psychiatry, 2021
Body Genome-wide Association Studies in Psychiatry - Current Perspectives Last decade was exciting time for human genetic studies. Genome-wide association studies (GWASs), used to examine the association of genotyped variants across the entire genome and
D. Smajlagic   +3 more
doaj   +1 more source

Evaluation of association of HNF1B variants with diverse cancers : collaborative analysis of data from 19 genome-wide association studies [PDF]

open access: yes, 2010
Background Genome-wide association studies have found type 2 diabetes-associated variants in the HNF1B gene to exhibit reciprocal associations with prostate cancer risk.
Tomlinson, IP   +280 more
core   +1 more source

Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data [PDF]

open access: yes, 2009
OBJECTIVE-This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes, association mid considered the implications for the etiological heterogeneity of type 2 diabetes ...
Timpson, NJ   +53 more
core   +1 more source

Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function [PDF]

open access: yes, 2014
Background: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.
Wenbo Tang (110161)   +617 more
core   +2 more sources

Biparental Crossing and QTL Mapping for Validation of Genome-Wide Association Studies

open access: yes, 2022
Association mapping (AM), also known as genome-wide association studies (GWAS), is increasingly being employed in crop plants for the identification of QTL/genes and marker–trait associations (MTAs) in natural populations.
Singh, R, Kulwal, PL
core   +1 more source

Simulating variance heterogeneity in quantitative genome wide association studies

open access: yesBMC Bioinformatics, 2018
Background Analyzing Variance heterogeneity in genome wide association studies (vGWAS) is an emerging approach for detecting genetic loci involved in gene-gene and gene-environment interactions.
Ahmad Al Kawam   +4 more
doaj   +1 more source

Status and prospects of genome‐wide association studies in plants

open access: yesThe Plant Genome, 2021
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous tool for the investigation of complex traits. In large part, this was fueled by advances in genomic technology, enabling us to examine genome‐wide genetic variants ...
Laura Tibbs Cortes   +2 more
doaj   +1 more source

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium [PDF]

open access: yes, 2011
Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease.
Marsit CJ   +934 more
core   +2 more sources

First genome-wide association study on anxiety-related behaviours in childhood [PDF]

open access: yes, 2013
Background: Twin studies have shown that anxiety in a general population sample of children involves both domain-general and trait-specific genetic effects.
Hanscombe, K.B.   +66 more
core   +1 more source

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies [PDF]

open access: yes, 2008
Testing one SNP at a time does not fully realise the potential of genome-wide association studies to identify multiple causal variants, which is a plausible scenario for many complex diseases.
Maria De Iorio   +18 more
core   +1 more source

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